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Free radicals derived from γ-radiolysis of water and AAPH thermolysis mediate oxidative crosslinking of eGFP involving Tyr-Tyr and Tyr-Cys bonds : the fluorescence of the protein is conserved only towards peroxyl radicals
(2020-04)
The enhanced green fluorescent protein (eGFP) is one of the most employed variants of fluorescent proteins. Nonetheless little is known about the oxidative modifications that this protein can undergo in the cellular milieu. ...
New insights into the reaction paths of hydroxyl radicals with purine moieties in DNA and double-stranded oligodeoxynucleotides
(Molecular Diversity Preservation International, 2019-10)
The reaction of hydroxyl radical (HO•) with DNA produces many primary reactive species and many lesions as final products. In this study, we have examined the optical spectra of intermediate species derived from the reaction ...
Rat ventral prostate xanthine oxidaseg-mediated metabolism of acetaldehyde to acetyl radical
(Sage Publications Ltd, 2009-04)
Alcohol drinking is known to lead to deleterious effects on prostate epithelial cells from humans and experimental animals. The understanding of the mechanisms underlying these effects is relevant to intraprostatic ethanol ...
Mechanism of tetrahydroxy-1,4-quinone cytotoxicity: Involvement of Ca2+ and H2O2 in the impairment of DNA replication and mitochondrial function
(Elsevier Science IncNew YorkEUA, 1996)
Biological and chemical study of fused tri- and tetracyclic indazoles and analogues with important antiparasitic activity
(2012)
A series of fused tri- and tetracyclic indazoles and analogues compounds (NID) with potential antiparasitic effects were studied using voltamperometric and spectroscopic techniques. Nitroanion radicals generated by cyclic ...
Major components of energy drinks (caffeine, taurine, and guarana) exert cytotoxic effects on human neuronal SH-SY5Y cells by decreasing reactive oxygen species production
(2013-06-12)
Scope. To elucidate the morphological and biochemical in vitro effects exerted by caffeine, taurine, and guarana, alone or in combination, since they are major components in energy drinks (EDs). Methods and Results. On ...
Major components of energy drinks (caffeine, taurine, and guarana) exert cytotoxic effects on human neuronal SH-SY5Y cells by decreasing reactive oxygen species production
(2013-06-12)
Scope. To elucidate the morphological and biochemical in vitro effects exerted by caffeine, taurine, and guarana, alone or in combination, since they are major components in energy drinks (EDs). Methods and Results. On ...
Oxidation of ethanol to acetaldehyde and free radicals by rat testicular microsomes
(Springer, 2005-01)
A large number of epidemiological studies evidencing that excessive alcohol consumption is associated with impaired testosterone production and testicular atrophy are available in the literature. One hypothesis to explain ...