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Molecular basis of ligand dissociation in β-adrenergic receptors
(Public Library of Science, 2011)
The important and diverse biological functions of β-adrenergic receptors (βARs) have promoted the search for compounds to stimulate or inhibit their activity. In this regard, unraveling the molecular basis of ligand ...
1-Benzyl-1,2,3,4-Tetrahydro-ss-Carboline as Channel Blocker of N-Methyl-d-Aspartate Receptors
(WILEY-BLACKWELL, COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA, 2012)
Tracking the Molecular Evolution of Calcium Permeability in a Nicotinic Acetylcholine Receptor
(Oxford University Press, 2014-09)
Nicotinic acetylcholine receptors are a family of ligand-gated nonselective cationic channels that participate in fundamental physiological processes at both the central and the peripheral nervous system. The extent of ...
Complex of luminescent europium containing bis(diphenylphosphine)oxide ligands
(Aptor Software, 2023)
Regulation of Neuronal Cav3.1 Channels by Cyclin-Dependent Kinase 5 (Cdk5)
(Public Library of Science, 2015)
Low voltage-activated (LVA) T-type Ca2+ channels activate in response to subthreshold
membrane depolarizations and therefore represent an important source of Ca2+ influx near
the resting membrane potential. In neurons, ...
Beyond hemostasis: a snake venom serine protease with potassium channel blocking and potential antitumor activities
(2020-12-01)
Snake venom serine proteases (SVSPs) are complex and multifunctional enzymes, acting primarily on hemostasis. In this work, we report the hitherto unknown inhibitory effect of a SVSP, named collinein-1, isolated from the ...
Fabrication of a guanidine ligand-based anion exchange monolithic stationary phase in a 3D printed polypropylene housing for protein chromatography
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2021-01-01)
A monolithic anion exchange support is synthesized based on the incorporation of γ -guanidinobutyric acid an alkaloid with three resonant amino groups- as ligand onto a poly(EDMA-co-GMA) monolith. The created monolithic ...