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Ryanodine receptor-mediated Ca2 release underlies iron-induced mitocondrial fission and stimulates mitocondrial Ca2 up take in primary hippocampal neurons
(Gaiti Hasan,Tata Institute of Fundamental Research, 2014)
Mountingevidenceindicatesthatironaccumulationimpairsbrainfunction.Wehavereportedpreviouslythatadditionofsub-lethalconcentrationsofirontoprimaryhippocampalneuronsproducesCa2+signalsandpromotescytoplasmicgenerationofreacti ...
Obesity induces upregulation of genes involved in myocardial Ca2+ handling
(Associação Brasileira de Divulgação Científica (ABRADIC), 2008-07-01)
Obesity is a complex multifactorial disorder that is often associated with cardiovascular diseases. Research on experimental models has suggested that cardiac dysfunction in obesity might be related to alterations in ...
Identification and electrophysiological properties of a sphingosine-dependent plasma membrane Ca2+ channel in Trypanosoma cruzi
(Wiley Blackwell Publishing, Inc, 2019-10)
Trypanosoma cruzi is the causative agent of Chagas disease. The only two drugs accepted for the treatment of this infection are benznidazole and nifurtimox, which are of limited use in the predominant chronic phase. On the ...
Inhibitory ryanodine prevents ryanodine receptor-mediated Ca2+ release without affecting endoplasmic reticulum Ca2+ content in primary hippocampal neurons
(2015)
Ryanodine is a cell permeant plant alkaloid that binds selectively and with high affinity to ryanodine receptor (RyR) Ca2+ release channels. Sub-micromolar ryanodine concentrations activate RyR channels while micromolar ...
Sodium-Calcium Exchanger Modulates the l-Glutamate Cai 2+ Signalling in Type-1 Cerebellar Astrocytes
(Advances in Experimental Medicine and Biology, 2017)
Silicon spraying alleviates calcium deficiency in tomato plants, but Ca-EDTA is toxic
(2020-12-01)
Background: The occurrence of calcium (Ca)-related disorders is common in tomato production and may be due to factors such as excess nitrogen (N) fertilization. Thus, Ca sprays are often applied as preventive measure to ...