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Dissociation of the effects of ethanol on memory, anxiety, and motor behavior in mice tested in the plus-maze discriminative avoidance task
(Springer, 2007-05-01)
Rationale Several studies have shown the amnestic effects of ethanol (ETOH). However, while memory tasks in rodents can be markedly influenced by anxiety-like behavior and motor function, ETOH induces anxiolysis and different ...
Alterações comportamentais induzidas pela ausência do ritmo circadiano de luz: Efeitos da luz constante ou escuro constante em comportamentos relacionados à depressão e na atividade locomotora em ratos
(2015-01-01)
Affective disorders have been linked to abnormal biological rhythms. Depression- and anxietyrelated behaviors can be altered following changes of daily periods of environmental light. The aim of this study was to investigate ...
Depression, anxiety-like behavior, and memory impairment in mice exposed to chitosan-coated zein nanoparticles
(2019-04-01)
The advent of biotechnology provided the synthesis of nanoproducts with diverse applications in the field of medicine, agriculture, food, among others. However, the toxicity of many nanoparticles (NP) currently used, which ...
Anxiolytic-like effects induced by blockade of transient receptor potential vanilloid type 1 (TRPV1) channels in the medial prefrontal cortex of rats
(SPRINGER, 2009)
The endocannabinoid anandamide, in addition to activating cannabinoid type 1 receptors (CB1), may act as an agonist at transient receptor potential vanilloid type 1 (TRPV1) channels. In the periaqueductal gray, CB1 activation ...
THE ANTERIOR CINGULATE CORTEX IS A TARGET STRUCTURE FOR THE ANXIOLYTIC-LIKE EFFECTS OF BENZODIAZEPINES ASSESSED BY REPEATED EXPOSURE TO THE ELEVATED PLUS MAZE AND FOS IMMUNOREACTIVITY
(PERGAMON-ELSEVIER SCIENCE LTD, 2009)
Prior experience with the elevated plus maze (EPM) increases the avoidance of rodents to the open arms and impairs the anxiolytic-like effects of benzodiazepines on the traditional behaviors evaluated upon re-exposure to ...
Enhancement of behavioral sensitization, anxiety-like behavior, and hippocampal and frontal cortical CREB levels following cocaine abstinence in mice exposed to cocaine during adolescence
(Public Library of ScienceSan Francisco, 2013-10-21)
Adolescence has been linked to greater risk-taking and novelty-seeking behavior and a higher prevalence of drug abuse and risk of relapse. Decreases in cyclic adenosine monophosphate response element binding protein (CREB) ...
GABA/benzodiazepine receptors in the ventromedial hypothalamic nucleus regulate both anxiety and panic-related defensive responses in the elevated T-maze
(Elsevier B.V., 2007-09-14)
It has been shown that facilitation of GABA-mediated neurotransmission in the medial nucleus of the amygdala and the dorsal periaqueductal gray (dPAG) inhibits the escape, but not the inhibitory avoidance response generated ...
Anxiogenic-like effect induced by TRPV1 receptor activation within the dorsal periaqueductal gray matter in mice
(2013-08-01)
Pharmacological manipulation of TRPV1 (Transient Receptor Potential Vanilloid type-1) receptors has been emerging as a novel target in the investigation of anxiety states. Here, we attempt to show the role played by the ...
Anxiogenic-like effect induced by TRPV1 receptor activation within the dorsal periaqueductal gray matter in mice
(2013-08-01)
Pharmacological manipulation of TRPV1 (Transient Receptor Potential Vanilloid type-1) receptors has been emerging as a novel target in the investigation of anxiety states. Here, we attempt to show the role played by the ...