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New insights from the use of pilocarpine and kainate models
(Elsevier B.V., 2002-06-01)
Local or systemic administration of pilocarpine and kainate in rodents leads to a pattern of repetitive limbic seizures and status epilepticus, which can last for several hours. A latent period follows status epilepticus ...
Are adverse effects of antiepileptic drugs different in symptomatic partial and idiopathic generalized epilepsies? the Portuguese-Brazilian validation of the Liverpool Adverse Events Profile
(Elsevier B.V., 2011-11-01)
We report the results of administration of the Portuguese-Brazilian translation of the Liverpool Adverse Events Profile (LAEP) to 100 patients (mean age = 34.5, SD = 12.12; 56 females), 61 with symptomatic partial epilepsy ...
Determination of levetiracetam in human plasma by dispersive liquid-liquid microextraction followed by gas chromatography-mass spectrometry
(Univ Sao Paulo, Inst Psiquiatria, 2016)
Levetiracetam (LEV) is an antiepileptic drug that is clinically effective in generalized and partial epilepsy syndromes. The use of this drug has been increasing in clinical practice and intra- or -interindividual variability ...
Novel long-term anticonvulsant treatment with gabapentin without causing memory impairment in mice
(Academic Press Inc Elsevier Science, 2010-02)
We previously reported that administration of a single dose of gabapentin (GBP) immediately after training improves memory of mice in an inhibitory avoidance task (IA), whereas GBP administered repeatedly for 7 days impairs ...
Pharmacovigilance in epileptic patients using antiepileptic drugsFarmacovigilância em pacientes com epilepsia em uso de drogas antiepilépticas
(Academia Brasileira de Neurologia - ABNEURO, 2006)
Use of antiepileptic drugs in children with brain tumors: A review for acute management
Patients with primary or secondary tumors in the central nervous system may have seizures resulting from direct tissue damage, metabolic abnormalities, infection, or toxic side effects of medications. In pediatric patients, ...