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NF-κB activation mediates crystal translocation and interstitial inflammation in adenine overload nephropathy
(American Physiological SocietyBethesda, 2013-07-15)
Adenine overload promotes intratubular crystal precipitation and interstitial nephritis. We showed recently that these abnormalities are strongly attenuated in mice knockout for Toll-like receptors-2, -4, MyD88, ASC, or ...
Diabetic nephropathy, autophagy and proximal tubule protein endocytic transport: A potentially harmful relationship
(Instituto de Histología y Embriología Dr. Mario Burgos, 2018-11)
Diabetic nephropathy (DN) is the most frequent cause of chronic renal failure. Until now, the pathophysiological mechanisms that determine its development and progression have not yet been elucidated. In the present study, ...
Electroacupuncture and Moxibustion Attenuate the Progression of Renal Disease in 5/6 Nephrectomized Rats
(Karger, 2008-01-01)
Background/Aim: Chronic kidney disease is a worldwide public health problem and the prevention of its progression is still a major challenge in nephrology. Specific therapies that inhibit or attenuate this process are ...
Losartan through Hsp70 Avoids Angiotensin II Induced Mesenchymal Epithelial Transition Proximal Tubule Cells from Spontaneously Hypertensive Rats
(Karger, 2019-10)
Renal injury related to hypertension is characterized by glomerular and tubulointerstitial damage. The overactivation of the renin-angiotensin system mainly by angiotensin II (AII) seems to be a main contributor to progressive ...
Papel das células NKT no modelo experimental de nefrite túbulo-intersticial induzida pela adenina
(Universidade Federal de São Paulo (UNIFESP), 2012-08-29)
As doenças que afetam o compartimento túbulo-intersticial renal são numerosas e variadas. A
patogênese das doenças renais envolve a participação de vários elementos da resposta imune. As células NKT constituem uma população ...
A Transversal Study of Biochemical Profile, Urinalysis, UPC, Electrolytes and Blood Pressure in Dogs with Chronic Kidney Disease
(Universidade Federal do Rio Grande do Sul, 2020)
A ação nefroprotetora de Passiflora edulis no diabetes induzido por estreptozotocina
(Universidade Federal do Rio Grande do NorteBrasilUFRNPROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS DA SAÚDE, 2022-07-28)
There is evidence that diabetic kidney disease is a frequent and severe diabetes
microvascular complication, thus requiring appropriate and continuous glycemic
control. Currently, insulin monotherapy is the traditional ...
A Transversal Study of Biochemical Profile, Urinalysis, UPC, Electrolytes and Blood Pressure in Dogs with Chronic Kidney Disease
(Univ Fed Rio Grande Do Sul, 2020-05-29)
Background: Chronic kidney disease (CKD) affects both dogs and cats, mainly elderly animals, due to tubulointerstitial inflammation associated with the increase of fibrosis through the excess deposition of extracellular ...
Leishmaniose visceral canina: estudo histológico e imuno-histoquímico renal com ênfase na fibropoese
(Universidade Federal de Minas GeraisUFMG, 2018-04-24)
Extracellular matrix (ECM) changes studies, in visceral leishmaniasis, are mainly those related to collagen deposition (fibropoese). There are studies in canine visceral leishmaniasis (LVC) showing intense fibropoiesis ...