Buscar
Mostrando ítems 51-60 de 464
Clonación y caracterización de precursores biosinteticos de secuencias peptídicas tipo endomorfinas
(2009-08-12)
ABSTRACT: Endomorphin-1 (EM-1) and endomorphin-2 (EM-2) are the latest opioid peptide ligands
discovered in the CNS of mammals that display the highest affinity and selectivity for the mu
opiate receptor. EM1-2 display ...
SARS-CoV-2 spike protein S1 activates Cx43 hemichannels and disturbs intracellular Ca2+ dynamics
(2023)
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes the ongoing coronavirus disease 2019 (COVID-19). An aspect of high uncertainty is whether the SARS-CoV-2 per se or the systemic inflammation ...
Diffuse reflectance spectroscopy and Optical polarization imaging of in-vivo biological tissue
(2010)
In vivo and in vitro evidence from animals suggesting that gap junctions (GJs) play a role in the spreading of epileptiform activity. We have examined the influence of the gap junction opener trimethylamine (TMA) and the ...
Impacto de andrógenos sobre a proliferação e atividade de fibroblastos e células epiteliais em cultura celular
(Universidade Estadual Paulista (UNESP), 2016)
Major contribution of the 3/6/7 class of TRPC channels to myocardial ischemia/reperfusion and cellular hypoxia/reoxygenation injuries
(National Academy of Sciences, 2017-05)
The injury phase after myocardial infarcts occurs during reperfusion and is a consequence of calcium release from internal stores combined with calcium entry, leading to cell death by apoptopic and necrotic processes. The ...
Acute exposure of a glyphosate-based herbicide affects the gills and liver of the Neotropical fish, Piaractus mesopotamicus
(Elsevier B.V., 2012-09-01)
The aim of this study was to determine the acute toxicity of Roundup (R) Ready (RR) in Piaractus mesopotamicus, and evaluate the effects on the morphology of the gills and liver of exposed surviving fish. Fish were exposed ...
Acute exposure of a glyphosate-based herbicide affects the gills and liver of the Neotropical fish, Piaractus mesopotamicus
(Elsevier B.V., 2012-09-01)
The aim of this study was to determine the acute toxicity of Roundup (R) Ready (RR) in Piaractus mesopotamicus, and evaluate the effects on the morphology of the gills and liver of exposed surviving fish. Fish were exposed ...
Voltage-Gated K+/Na(+)Channels and Scorpion Venom Toxins in Cancer
(Frontiers Media, 2020)
Ion channels have recently been recognized as novel therapeutic targets in cancer research since they are overexpressed in different histological tissues, and their activity is linked to proliferation, tumor progression, ...
Effects of Fluoride on Submandibular Glands of Mice: Changes in Oxidative Biochemistry, Proteomic Profile, and Genotoxicity
(2021-09-27)
Although fluoride (F) is well-known to prevent dental caries, changes in cell processes in different tissues have been associated with its excessive exposure. Thus, this study aimed to evaluate the effects of F exposure ...