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Regulatory effects of estetrol on the endothelial plasminogen pathway and endothelial cell migration
(Elsevier Ireland, 2017-05)
BACKGROUND: Estetrol (E4) is a natural estrogen produced solely during human pregnancy. E4 is suitable for clinical use since it acts as a selective estrogen receptor modulator. In clinical trials E4 has been seen to have ...
Raloxifeno e osteoporose: revisão de um novo modulador seletivo do receptor de estrógeno
(Sociedade Brasileira de Endocrinologia e Metabologia, 1999-12-01)
Raloxifene is a selective estrogen receptor modulator of second generation with agonist effect in the bone, cardiovascular system, and antagonist effect in the breast and uterus. The tissue selectivity of raloxifene occurs ...
Helix 12 Dynamics and Thyroid Hormone Receptor Activity: Experimental and Molecular Dynamics Studies of Ile280 Mutants
(Academic Press Ltd- Elsevier Science LtdLondonInglaterra, 2011)
Participação dos receptores para esteróides ovarianos na ação da kisspeptina sobre neurônios dopaminérgicos e secreção de prolactina
(Universidade Federal de Minas GeraisUFMG, 2013-04-03)
We have shown that kisspeptin stimulates prolactin (PRL) secretion in an estradiol-dependent manner through inhibition of dopaminergic terminals in the median eminence (ME). The effects of estradiol may occur via estrogen ...
Continuous Exposure of Breast Cancer Cells to Tamoxifen Upregulates GPER-1 and Increases Cell Proliferation
(2020-09-30)
GPER-1 is a novel membrane sited G protein-coupled estrogen receptor. Clinical studies have shown that patients suffering an estrogen receptor α (ERα)/GPER-1 positive, breast cancer have a lower survival rate than those ...