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Identification of two surface proteins from C6/36 cells that bind dengue type 4 virus
(Journal of Virology, 1997-06-18)
Dengue viruses infect cells by attaching to a surface receptor, probably through the envelope (E) glycoprotein, located on the surface of the viral membrane. However, the identity of the dengue virus receptor in the mosquito ...
A family-based approach reveals the function of residues in the nuclear receptor ligand-binding domain
(Elsevier B.V., 2004-08-06)
Literature studies, 3D structure data, and a series of sequence analysis techniques were combined to reveal important residues in the structure and function of the ligand-binding domain of nuclear hormone receptors. A ...
Differential effects of exercise on brain opioid receptor binding and activation in rats
(Wiley-Blackwell, 2015-01-01)
Physical exercise stimulates the release of endogenous opioid peptides supposed to be responsible for changes in mood, anxiety, and performance. Exercise alters sensitivity to these effects that modify the efficacy at the ...
N-SUBSTITUTION AND α1-ADRENERGIC RECEPTOR AFFINITY OF LAUDANOSINE ANALOGUES
(Sociedad Chilena de Química, 2006-09)
Benzyltetrahydroisoquinoline (BTHIQ) molecules are able to adopt widely differing conformations that depend on the presence or absence of N-substituents.
To assess the possible role of BTHIQ conformation on the affinity ...
N-SUBSTITUTION AND a,-ADRENERGIC RECEPTOR AFFlNITV OJi'LAUDANOSINE ANALOGUES
(Sociedad Chilena de Química, 2006)
Benzyltetrahydroisoquinoline (BTHIQ) molecules are able to adopt widely differing conformations that depend on the presence or absence of N-substituents.
To assess the possible role of BTHIQ conformation on the affinity ...
Inhibitory mechanisms and binding site location for serotonin selective reuptake inhibitors on nicotinic acetylcholine receptors
(Pergamon-Elsevier Science Ltd, 2010-05)
Functional and structural approaches were used to examine the inhibitory mechanisms and binding site location for fluoxetine and paroxetine, two serotonin selective reuptake inhibitors, on nicotinic acetylcholine receptors ...
Calcitonin modifies ligand binding to muscarinic receptor in CNS membranes
(Elsevier Science, 2000-03)
Calcitonin (CT) is a peptide produced by the thyroid gland, whose best described role is to prevent bone reabsorption, though it also participates in other biological functions through both central and peripheral mechanisms. ...
Receptor-binding variants of H3N2 influenza A viruses: characterization of their sialidase activity towards different substrates
(Instituto de Ci??ncias da Sa??de/ Universidade Federal da Bahia, 2004-01)
Distinct binding mode of I-125-AngII to AT(1) receptor without the Cys(18)-Cys(274) disulfide bridge
(Elsevier B.V., 2009-11-27)
Previous studies on angiotensin II (AngII) AT(1) receptor function have revealed that the N-terminal residues of AngII may modulate receptor activation by binding at the receptor extracellular site. A remarkable feature ...