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The pathogenic role of c‑Kit+ mast cells in the spinal motor neuron‑vascular niche in ALS
(Springer Nature, 2021)
Degeneration of motor neurons, glial cell reactivity, and vascular alterations in the CNS are important neuropathological features of amyotrophic lateral sclerosis (ALS). Immune cells trafficking from the blood also ...
Genotype–phenotype correlation of SMN locus genes in spinal muscular atrophy children from Argentina
(Elsevier, 2016-11)
Background/Purpose: Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disorder, considered one of the leading causes of infant mortality. It is caused by mutations in the SMN1 gene. A highly homologous ...
Interrogating interneurone function using threshold tracking of the H reflex in healthy subjects and patients with motor neurone disease
(Elsevier, 2020)
Objective: The excitability of the lower motoneurone pool is traditionally tested using the H
reflex and a constant-stimulus paradigm, which measures changes in the amplitude of the reflex
response. This technique has ...
Drosophila Atlastin in motor neurons is required for locomotion and presynaptic function
(Company of Biologists Ltd., 2017)
Hereditary spastic paraplegias (HSPs) are characterized by spasticity and weakness of the lower limbs, resulting from length-dependent axonopathy of the corticospinal tracts. In humans, the HSP-related atlastin genes ...
Long lasting structural changes in primary motor cortex after motor skill learning: a behavioural and stereological study
(Sociedad de Biología de Chile, 2008)
The reactions of specific neuron types to intestinal ischemia in the guinea pig enteric nervous system
(SPRINGER, 2009)
Damage following ischemia and reperfusion (I/R) is common in the intestine and can be caused during abdominal surgery, in several disease states and following intestinal transplantation. Most studies have concentrated on ...
Zinc deficiency in neuronal biology
(Wiley, 2007-05)
Adverse nutritional and environmental conditions during early development can irreversibly affect the nervous system. Zinc (Zn) deficiency associated with inadequate Zn intake and undernutrition is frequent throughout the ...
Temperature manipulation of neuronal dynamics in a forebrain motor control nucleus
(Public Library of Science, 2017-08)
Different neuronal types within brain motor areas contribute to the generation of complex motor behaviors. A widely studied songbird forebrain nucleus (HVC) has been recognized as fundamental in shaping the precise timing ...