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Mostrando ítems 51-60 de 1021
Síndrome de Noonan: do fenótipo à terapêutica com hormônio de crescimento
(Sociedade Brasileira de Endocrinologia e Metabologia, 2008)
A síndrome de Noonan (SN) é uma síndrome genética comum que constitui importante diagnóstico diferencial em pacientes com baixa estatura, atraso puberal ou criptorquidia. A SN apresenta grande variabilidade fenotípica e é ...
Inhibiting autophagy to prevent drug resistance and improve anti-tumor therapy
(2021-01-15)
Cytotoxic drugs remain the first-line option for cancer therapy but the development of drug-resistance by tumor cells represents a primary obstacle for successful chemotherapy. Autophagy is a physiological mechanism of ...
Pharmacologic inhibition of the CK2-mediated phosphorylation of B23/NPM in cancer cells selectively modulates genes related to protein synthesis, energetic metabolism, and ribosomal biogenesis
(Springer, 2015-06)
B23/NPM is a multifunctional nucleolar protein frequently overexpressed, mutated, or rearranged in neoplastic tissues. B23/NPM is involved in diverse biological processes and is mainly regulated by heteroligomer association ...
High doses of vitamin d as a rational pharmacologic approach in the covid-19 pandemic
(American Physiological Society, 2020-07)
COVID-19 pandemic reached most of the countries of the world causing death as a result of the inflammatory storm, oxidative imbalance from the severe acute respiratory syndrome. Many laboratories fight against the clock ...
Vitamin D supplementation as a rational pharmacological approach in the covid-19 pandemic
(American Physiological Society, 2020-09)
The COVID-19 pandemic has reached most of the countries worldwide causing death, which often results from an inflammatory storm associated with severe acute respiratory syndrome (SARS). This has prompted researchers to ...
Frecuencia de tromboembolismo venoso en pacientes hospitalizados con cáncer. Factores de riesgo y eficacia de la tromboprofilaxis farmacológica
(SOC MEDICA SANTIAGO, 2008-12)
Hospitalized patients with cancer have a high risk
of venous thromboembolism (VTE). Aim: To study the frequency of VTE and its risk factors in
hospitalized patients with cancer. Material and methods: Retrospective analysis ...
Cell culture models and pharmacological perspective for the study of breast cancer markers.
(The International Federation of Clinical Chemistry and Laboratory Medicine, 2019)
Diseño de un modelo bioinformática para la detección, identificación y clasificación de genes codificantes de b-lactamasas, como herramienta para el cruce de datos moleculares con datos clínicos
(Revista Colombiana de Ciencias Químico Farmacéuticas, 2007)
El seguimiento epidemiológico y farmacológico de la resistencia a antibióticos b-lactámicos mediada por la presencia de b-lactamasas requiere identificación precisa, lo cual es posible mediante la secuencia del gen, que ...