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Mucosal immune tolerance at the ocular surface in health and disease
(Wiley Blackwell Publishing, Inc, 2017-04)
The ocular surface is constantly exposed to environmental irritants, allergens and pathogens, against which it can mount a prompt immune response to preserve its integrity. But to avoid unnecessary inflammation, the ocular ...
Modulation of established murine collagen-induced arthritis by a single inoculation of short-term lipopolysaccharide-stimulated dendritic cells
(2008)
Background: The use of regulatory or immature dendritic cells (DCs) as tools for modulating experimental rheumatoid arthritis is very recent. Tumour necrosis factor (TNF)-stimulated DCs have been shown to restore tolerance ...
Transferência adotiva dos efeitos indiretos da exposição parenteral a antígenos tolerados
(Universidade Federal de Minas GeraisUFMG, 2005-02-23)
Parenteral exposure to antigens to which oral tolerance had been previously induced affects (inhibits) immunological activities connected to unrelated antigens, a phenomenon we have called indirect effects of oral tolerance ...
Lifelong Maintenance of Oral Tolerance and Immunity Profiles in Mice Depends on Early Exposure to Antigen
(Blackwell Scientific Publications, 2019)
Oral tolerance correlates with high levels of lymphocyte activity
(Academic Press, 2013)
Update on Aire and thymic negative selection
(Wiley, 2018)
Tolerance Induction at the Early Maternal–Placental Interface Through Selective Cell Recruitment and Targeting by Immune Polypeptides
(Wiley, 2013-02)
Pregnancy challenges immune cells and immunomodulatory circuits of the mother and the developing fetus to dynamically adapt to each other in an homeostatic and tolerant environment for fetal growth. This entails the ...
Monocyte-derived dendritic cells from breast cancer patients are biased to induce CD4(+)CD25(+)Foxp3(+) regulatory T cells
(FEDERATION AMER SOC EXP BIOLBETHESDA, 2012)
DCs orchestrate immune responses contributing to the pattern of response developed. In cancer, DCs may play a dysfunctional role in the induction of CD4(+)CD25(+) Foxp3(+) Tregs, contributing to immune evasion. We show ...