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Histological analysis of effects of 24% EDTA gel for nonsurgical treatment of periodontal tissues
(Nihon University School of Dentistry, 2006)
The aim of this study was to investigate, by means of histological and histomorphometric analysis, the effects of 24% ethylenediaminetetraacetic acid (EDTA) gel in periodontal tissue when used in combination with conventional ...
Structural basis for inhibition of cyclin-dependent kinase 9 by flavopiridol
(2002-07-08)
Flavopiridol has been shown to potently inhibit CDK1 and 2 (cyclin-dependent kinases 1 and 2) and most recently it has been found that it also inhibits CDK9. The complex CDK9-cyclin T1 controls the elongation phase of ...
Structural basis for inhibition of cyclin-dependent kinase 9 by flavopiridol
(2002-07-08)
Flavopiridol has been shown to potently inhibit CDK1 and 2 (cyclin-dependent kinases 1 and 2) and most recently it has been found that it also inhibits CDK9. The complex CDK9-cyclin T1 controls the elongation phase of ...
Structural Insights into Human Peroxisome Proliferator Activated Receptor Delta (PPAR-Delta) Selective Ligand Binding
(PUBLIC LIBRARY SCIENCESAN FRANCISCO, 2012)
Peroxisome proliferator activated receptors (PPARs delta, alpha and gamma) are closely related transcription factors that exert distinct effects on fatty acid and glucose metabolism, cardiac disease, inflammatory response ...
Strategies for developing multi-epitope, subunit-based, chemically synthesized anti-malarial vaccines
Introduction•P. falciparum invasion of RBCs•Merozoite proteins involved in invading erythrocytes•Erythrocyte proteins involved in merozoite invasionThe state of current worldwide anti?malarial vaccine approaches • A ...
Structure and Dynamics Study of LeuT Using the Markov State Model and Perturbation Response Scanning Reveals Distinct Ion Induced Conformational States
(American Chemical Society, 2016-06)
The bacterial leucine transporter (LeuT), a close homologue of the eukaryote monoamine transporters (MATs), currently serves as a powerful template for computer simulations of MATs. Transport of the amino acid leucine ...
Docking molecular aplicado ao estudo da formação de complexos entre análogos de resveratrol e derivados de 1,2,3-triazol e a enzima COX-2
(Universidade Federal de São CarlosBRUFSCarPrograma de Pós-Graduação em Biotecnologia - PPGBiotec, 2011-12-14)
Prostaglandin H synthases (PGHS), or cyclooxygenases (COX), are known to exist in at least two isoforms, COX-1 and COX-2, encoded by different genes. COX s play a central role in the inflammatory cascade by converting ...
Adjuvant Therapy with 1% Alendronate Gel for Experimental Periodontitis Treatment in Rats
(2021-01-01)
Purpose: The aim of this study was to evaluate the effects of locally delivered 1% alendronate (ALN) gel used as an adjunct to non-invasive periodontal therapy. Methods: Ligature-induced periodontitis was performed in 96 ...