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Effect of enzymatic pro-oxidant and antioxidant systems on bovine oocyte in vitro maturation
(Inst Zootechniki, 2021-09)
The role of reactive oxygen species (ROS) during oocyte in vitro maturation (IVM) is still controversial. Although an increase in ROS production may cause deleterious effects in cells, these reactive species may also act ...
Xanthine Oxidase Activation Modulates the Endothelial (Vascular) Dysfunction Related to HgCl2 Exposure Plus Myocardial Infarction in Rats
(Universidade Federal de Minas GeraisBrasilMEDICINA - FACULDADE DE MEDICINAUFMG, 2017)
A exposição a metais pesados está associada a doenças cardiovasculares, como infarto do miocárdio (IM). A disfunção vascular está relacionada tanto às causas quanto às consequências do IM. Investigamos se a exposição ...
Reduced neuronal nitric oxide synthase expression contributes to cardiac oxidative stress and nitroso-redox imbalance in ob/ob mice
(Elsevier B.V., 2007-05-01)
Disruption of leptin signaling in the heart may contribute to obesity-related cardiac disease, as leptin deficient (ob/ob) mice display cardiac hypertrophy, increased cardiac apoptosis and reduced survival. Since leptin ...
Kinetic and structural studies of aldehyde oxidoreductase from Desulfovibrio gigas reveal a dithiolene-based chemistry for enzyme activation and inhibition by H2O2
(Public Library of Science, 2013-12-31)
Mononuclear Mo-containing enzymes of the xanthine oxidase (XO) family catalyze the oxidative hydroxylation of aldehydes and heterocyclic compounds. The molybdenum active site shows a distorted square-pyramidal geometry in ...
Fatty acid nitroalkenes ameliorate glucose intolerance and pulmonary hypertension in high-fat diet-induced obesity
(Oxford University Press, 2014-01)
Aims Obesity is a risk factor for diabetes and cardiovascular diseases, with the incidence of these disorders becoming epidemic. Pathogenic responses to obesity have been ascribed to adipose tissue (AT) dysfunction that ...
Determinación del potencial inhibitorio de la fracción alcaloidal de Psychotria pilosa sobre xantina oxidasa y radical superóxido mediante autografía.
(Escuela Superior Politécnica de Chimborazo, 2019-12-06)
The research aimed to determine the inhibitory potential of the alkaloidal fraction of P.pilosa on xanthine oxidase and superoxide radical by autography. The alkaloidal extract of the P. pilosa leaves was obtained from ...
The Control of Reactive Oxygen Species Influences Porcine Oocyte In Vitro Maturation
(Wiley Blackwell Publishing, Inc, 2015-04)
The aim of this study was to examine the effect of varying intracellular reactive oxygen species (ROS) levels during oocyte in vitro maturation with enzymatic ROS production systems (xanthine + xanthine oxidase or xanthine ...