Buscar
Mostrando ítems 51-60 de 134
Immunophilins FKBP51 and FKBP52
(MDPI, 2019)
Immunophilins are a family of proteins whose signature domain is the peptidylprolyl-isomerase domain. High molecular weight immunophilins are characterized by the additional presence of tetratricopeptide-repeats (TPR) ...
Telomerasa y Telómero: Su estructura y dinámica en salud y enfermedadTelomerase and telomere: their structure and dynamics in health and disease
(Medicina (Buenos Aires), 2014-01)
La telomerasa es la enzima responsable del mantenimiento de la longitud de los telómeros mediante la adición de secuencias repetitivas ricas en guanina, y su actividad se observa principalmente en gametos, células madre y ...
The potential role of epigenetics on multipotent cell differentiation capacity of mesenchymal stromal cells
(Wiley, 2013-01)
Human umbilical cord perivascular cells (HUCPVCs) are a readily available source of mesenchymal stromal cells (MSCs) for cell therapy. We were interested in understanding how differences from human bone marrow (BM)-derived ...
Brief report: The potential role of epigenetics on multipotent cell differentiation capacity of mesenchymal stromal cells
(Alphamed Press, 2013-01)
Human umbilical cord perivascular cells (HUCPVCs) are a readily available source of mesenchymal stromal cells (MSCs) for cell therapy. We were interested in understanding how differences from human bone marrow (BM)-derived ...
Distinct tumor suppressor mechanisms evolve in rodent species that differ in size and lifespan
(WILEY-BLACKWELL PUBLISHING, INC, 2008)
Large, long-lived species experience more lifetime cell divisions and hence a greater risk of spontaneous tumor formation than smaller, short-lived species. Large, long-lived species are thus expected to evolve more elaborate ...
Gravity and Telomeres
(Austin Publishing Group, 2018-08)
Telomere shortening is a well-known process that is proposed to influence the pace of aging in every living being. On the other hand, telomere lengthening seems to be restricted to pluripotent cells and adult stem cell ...
Caracterização molecular de RNAs teloméricos não codantes em Leishmania major
(Universidade Estadual Paulista (Unesp), 2018-03-23)
Os protozoários do gênero Leishmania causam leishmaniose, uma doença tropical negligenciada, que se apresenta de diferentes formas clínicas e que acomete milhões de pessoas no Brasil e no mundo. Até o momento não existe ...
A calmodulin-like protein (LCALA) is a new Leishmania amazonensis candidate for telomere end-binding protein
(2017-11-01)
Background Leishmania spp. telomeres are composed of 5′-TTAGGG-3′ repeats associated with proteins. We have previously identified LaRbp38 and LaRPA-1 as proteins that bind the G-rich telomeric strand. At that time, we had ...
Efeito modulatório do barbatimão (Stryphnodendron adstringens (Mart.) Coville) em marcadores citofuncionais de fibroblastos humanos senescentes: estudo in vitro
(Universidade Federal de Santa MariaBrasilCiências da SaúdeUFSMPrograma de Pós-Graduação em GerontologiaCentro de Educação Física e Desportos, 2018-07-23)
Introduction: the skin, with aging, undergoes a decrease in functions responding more slowly and partially to maintenance and regeneration processes. Because it is a complex phenomenon, many issues are involved in the onset ...