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Modulation of host cell signaling pathways as a therapeutic approach in periodontal disease
(Universidade de São Paulo (USP), Faculdade de Odontologia de Bauru, 2012-03-01)
Recently, new treatment approaches have been developed to target the host component of periodontal disease. This review aims at providing updated information on host-modulating therapies, focusing on treatment strategies ...
Modulation of host cell signaling pathways as a therapeutic approach in periodontal disease
(2012-01-01)
Recently, new treatment approaches have been developed to target the host component of periodontal disease. This review aims at providing updated information on host-modulating therapies, focusing on treatment strategies ...
Ultrasensitivity in signaling cascades revisited: Linking local and global ultrasensitivity estimations
(Public Library of Science, 2017-06)
Ultrasensitive response motifs, capable of converting graded stimuli into binary responses, are well-conserved in signal transduction networks. Although it has been shown that a cascade arrangement of multiple ultrasensitive ...
Understanding signaling cascades in melanoma
(Wiley, 2008)
Understanding regulatory pathways involved in melanoma development and progression has advanced significantly in recent years. It is now appreciated that melanoma is the result of complex changes in multiple signaling ...
Expression of SOCS1, SOCS2, and SOCS3 in growth hormone-stimulated skin fibroblasts from children with idiopathic short stature
(2012)
Background/aim: Possible etiologies of idiopathic short stature (ISS) include a range of conditions, some of which may be caused by defects in the modulation of the growth hormone (GH)-signaling pathway. The Janus kinase/signal ...