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S-nitrosation of beta-catenin and p120 catenin a novel regulatory mechanism in endothelial hyperpermeabilityCIRCULATION RESEARCHCIRC RES
(LIPPINCOTT WILLIAMS & WILKINS, 2016)
Naringin attenuates liver damage in streptozotocin-induced diabetic rats
(Elsevier France-editions Scientifiques Medicales Elsevier, 2018-09)
The aim of this study was to evaluate whether NAR has a hepatoprotective role in a model of STZ-induced diabetes and to elucidate the underlying mechanisms triggered by the flavonoid. Male Wistar rats were divided into ...
Retirada do tratamento com atorvastatina e o dano por espécies reativas no córtex cerebral de ratos
(Universidade Federal de Santa MariaBRFarmacologiaUFSMPrograma de Pós-Graduação em Farmacologia, 2013-02-27)
Statins are drugs used in dislipidemias treatment. These agents are reversible inhibitors of the rate-limiting enzyme in cholesterol biosynthesis,the 3-hydroxy-3-methylglutaryl-coenzyme A reductase, and preventing de ...
Avaliação do estresse oxidativo e nitrosativo no fígado de ratas senescentes tratadas com frutose
(Universidade Federal de São Paulo (UNIFESP), 2017-07-31)
Introduction: Ageing is a multifactorial process caused by the progressive decline in physiological functions. According to IBGE (Instituto Brasileiro de Geografia e Estatística), Brazil's current population has 23.5 million ...
Cx46 hemichannel modulation by nitric oxide: Role of the fourth transmembrane helix cysteine and its possible involvement in cataract formation.
(2019)
Under normal conditions, connexin (Cx) hemichannels have a low open probability, which can increase under pathological conditions. Since hemichannels are permeable to relatively large molecules, their exacerbated activity ...