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Mostrando ítems 51-60 de 82
Chaperoning α7 neuronal nicotinic acetylcholine receptors
(Elsevier B.V., 2012)
Abstract: The α7 subtype of nicotinic acetylcholine receptors (AChRs) is one of the most abundant members of the Cys-loop family of receptors present in the central nervous system. It participates in various physiological ...
Quercetin antagonism of GABAAρ1 receptors is prevented by ascorbic acid through a redox-independent mechanism
(Elsevier, 2013-08)
Quercetin is a natural flavonoid widely distributed in plants that acts as a neuroprotective agent and modulates the activity of different synaptic receptors and ion channels, including the ionotropic GABA receptors. ...
Modulación de los receptores GABA Ap1 por especies reactivas del oxígeno y benzodiazepinasModulation of GABA Ap1 receptors by reactive oxygen species and benzodiazepines
(Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires, 2015)
Anesthetics as chemical tools to study the structure and function of nicotinic acetylcholine receptors
(Bentham Science Publishers, 2005-10)
The nicotinic acetylcholine receptor (AChR) is the archetype of the Cys-loop ligand-gated ion channel'receptor superfamily. Noncompetitive antagonists inhibit the AChR without interacting directly with agonist sites. Among ...
Neurotransmitter GABA Activates Muscle but not a7 Nicotinic Receptors
(American Society For Pharmacology And Experimental Therapeutics, 2015-03)
Cys-loop receptors are neurotransmitter-activated ion channels involved in synaptic and extrasynaptic transmission in the brain and are also present in non-neuronal cells. As GABAA and nicotinic receptors (nAChR) belong ...
Single-Channel Kinetic Analysis for Activation and Desensitization of Homomeric 5-HT3A Receptors
(Cell Press, 2009-09)
The 5-HT3A receptor is a member of the Cys-loop family of ligand-gated ion channels. To perform kinetic analysis, we mutated the 5-HT3A subunit to obtain a high-conductance form so that single-channel currents can be ...