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Membrane targeting peptides toward antileishmanial activity: Design, structural determination and mechanism of interaction
(Elsevier B.V., 2017-11-01)
Background: Leishmaniasis threatens poor areas population worldwide, requiring new drugs less prone to resistance development. Antimicrobial peptides with antileishmanial activity are considered among fulfilling alternatives, ...
Lipid-packing perturbation of model membranes by pH-responsive antimicrobial peptides
(2017-10-01)
The indiscriminate use of conventional antibiotics is leading to an increase in the number of resistant bacterial strains, motivating the search for new compounds to overcome this challenging problem. Antimicrobial peptides, ...
Rational design and synthesis of modified natural peptides from Boana pulchella (anura) as acetylcholinesterase inhibitors and antioxidants
(Springer, 2021-11)
The use of acetylcholinesterase (AChE) inhibitors, antioxidants or multitarget compounds are among the main strategies against Alzheimer’s disease (AD). Between AChE inhibitors, those targeting the peripheral anionic site ...
Effect of phosphoric acid on the degradation of human dentin matrix
(2013-01-01)
This study determined if dentin proteases are denatured by phosphoric acid (PA) used in etch-and-rinse dentin adhesives. Dentin beams were completely demineralized with EDTA for 30 days. We acid-etched experimental groups ...
Effect of phosphoric acid on the degradation of human dentin matrix
(2013-01-01)
This study determined if dentin proteases are denatured by phosphoric acid (PA) used in etch-and-rinse dentin adhesives. Dentin beams were completely demineralized with EDTA for 30 days. We acid-etched experimental groups ...
Highlights in peptide nanoparticle carriers intended to oral diseases
(Bentham Science Publ Ltd, 2015)
Innovative Mucoadhesive Precursor of Liquid Crystalline System Loading Anti-Gellatinolytic Peptide for Topical Treatment of Oral Cancer
(Amer Scientific Publishers, 2021-02-01)
Current researches report an actual benefit of a treatment for oral cancer via inhibition of proteolytic matrix metalloproteinases (MPP) with a peptide drug, called CTT1. However, peptides present poor oral bioavailability. ...
Highlights in peptide nanoparticle carriers intended to oral diseases
(Bentham Science Publ Ltd, 2015)