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Osteoglycin post-transcriptional regulation by miR-155 induces cellular architecture changes in H9c2 cardiomyoblasts
(Elsevier B.V., 2018-11-15)
Several studies have demonstrated dysregulated cardiac microRNAs (miRNAs) following cardiac stress and development of cardiac hypertrophy and failure. miRNAs are also differentially expressed in the inflammation that occurs ...
Identification of novel candidate genes for globin regulation in erythroid cells containing large deletions of the human beta-globin gene cluster
(Academic Press Inc Elsevier ScienceSan DiegoEUA, 2006)
The endoplasmic reticulum-associated mRNA-binding proteins ERBP1 and ERBP2 interact in bloodstream-form Trypanosoma brucei
(PeerJ Inc, 2020-02)
Kinetoplastids rely heavily on post-transcriptional mechanisms for control of gene expression, and on RNA-binding proteins that regulate mRNA splicing, translation and decay. Trypanosoma brucei ERBP1 (Tb927.10.14150) and ...
The RNA-binding protein TcUBP1 up-regulates an RNA regulon for a cell surface–associated Trypanosoma cruzi glycoprotein and promotes parasite infectivity
(American Society for Biochemistry and Molecular Biology, 2019-06)
The regulation of transcription in trypanosomes is unusual. To modulate protein synthesis during their complex developmental stages, these unicellular microorganisms rely largely on post-transcriptional gene expression ...
Hfq modulates global protein pattern and stress response in Bordetella pertussis
(Elsevier Science, 2019-10)
B. pertussis is the etiological agent of whooping cough, a highly contagious respiratory disease which remains uncontrolled worldwide. Understanding how this pathogen responds to the environmental changes and adapts to ...
Integrated analysis of microRNA regulation and its interaction with mechanisms of epigenetic regulation in the etiology of systemic lupus erythematosus
(Public Library of ScienceFacultad de Ciencias Básicas y Biomédicas, 2019)
The aim of this study was to identity in silico the relationships among microRNAs (miRNAs)
and genes encoding transcription factors, ubiquitylation, DNA methylation, and histone
modifications in systemic lupus erythematosus ...
Calcineurin phosphatase as a negative regulator of fear memory in hippocampus: Control on nuclear factor-κB signaling in consolidation and reconsolidation
(Wiley, 2014-12)
Protein phosphatases are important regulators of neural plasticity and memory. Some studies support that the Ca2+/calmodulin-dependent phosphatase calcineurin (CaN) is, on the one hand, a negative regulator of memory ...
ABC transporters: Regulation and association with multidrug resistance in hepatocellular carcinoma and colorectal carcinoma
(Bentham Science Publishers, 2017-11)
For most cancers, the treatment of choice is still chemotherapy despite its severe adverse effects, systemic toxicity and limited efficacy due to the development of multidrug resistance (MDR). MDR leads to chemotherapy ...