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The reinstatement of amphetamine-induced place preference is long-lasting and related to decreased expression of AMPA receptors in the nucleus accumbens
(Pergamon-Elsevier B.V. Ltd, 2008-01-24)
A great deal of effort has been devoted to elucidating the psychopharmacology underlying addiction and relapse. Long-term neuroadaptations in glutamate transmission seem to be of great relevance for relapse to stimulant ...
Stress induces behavioral sensitization, increases nicotine-seeking behavior and leads to a decrease of CREB in the nucleus accumbens
(Pergamon-Elsevier B.V. Ltd, 2012-05-01)
Experimental evidence shows that exposure to stress engenders behavioral sensitization and increases drug-seeking and leads to intense drug taking. However the molecular mechanisms involved in these processes is not well ...
Stress-induced locomotor sensitization to amphetamine in adult, but not in adolescent rats, is associated with increased expression of ΔFosB in the nucleus accumbens
(2016-09-12)
While clinical and pre-clinical evidence suggests that adolescence is a risk period for the development of addiction, the underlying neural mechanisms are largely unknown. Stress during adolescence has a huge influence on ...
Centralization of noxious stimulus-induced analgesia (NSIA) is related to activity at inhibitory synapses in the spinal cord
(Elsevier Science BvAmsterdamHolanda, 2009)
Adaptations in nucleus accumbens circuitry during opioid withdrawal associated with persistence of noxious stimulus-induced antinociception in the rat
(Churchill LivingstoneEdinburghEscócia, 2003)
Cross-sensitization between cocaine and acute restraint stress is associated with sensitized dopamine but not glutamate release in the nucleus accumbens
(Wiley Blackwell Publishing, Inc, 2013-03)
Repeated administration of psychostimulant drugs or stress can elicit a sensitized response to the stimulating and reinforcing properties of the drug. Here we explore the mechanisms in the nucleus accumbens (NAc) whereby ...
Gene and antisense delivery in alcoholism research
(Lippincott Williams and Wilkins, 2002)
This article represents the proceedings of a symposium at the 2001 annual meeting of the Research Society on Alcoholism in Montreal, Canada. Drs. Yedy Israel and Fulton Crews were organizers and co-chairpersons. The ...
Auditory stimulation by exposure to melodic music increases dopamine and serotonin activities in rat forebrain areas linked to reward and motor control
(Universidade Federal de Minas GeraisBrasilEEF - DEPARTAMENTO DE EDUCAÇÃO FÍSICAICB - DEPARTAMENTO DE FISIOLOGIA E BIOFÍSICAUFMG, 2018-04)
Avaliação neuroquímica e comportamental em ratos submetidos ao modelo de depressão induzida por extinçãoNeurochemical and behavioural assessment in rats submitted to the extinction-induced depression model
(Universidade Estadual de MaringáBrasilPrograma de Pós-Graduação em Ciências FarmacêuticasUEMMaringá, PRDepartamento de Farmácia, 2018)
Efecto de la inhibición de la amida hidrolasa de ácidos grasos por una nueva macamida sintética MACOMCH-01 en el comportamiento tipo depresivo a través de la modulación de la señalización dopaminérgica mesolímbica de ratones BALB/c
(Universidad Peruana Cayetano HerediaPE, 2022)
MACOMCH-01 es una macamida semisintética que ha demostrado, in-vitro, actividad inhibitoria de amida hidrolasa de ácidos grasos (FAAH), enzima encargada del metabolismo de endocannabinoides. Este hecho sugiere un potencial ...