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Interactions of pannexin 1 with NMDA and P2X7 receptors in central nervous system pathologies: Possible role on chronic pain
(Elsevier, 2015)
Pannexin 1 (Panx1) is a glycoprotein that acts as a membrane channel in a wide variety of tissues in mammals. In the central nervous system (CNS) Panx1 is expressed in neurons, astrocytes and microglia, participating in ...
Estudo da analgesia induzida por administração de antagonista de receptores NMDA – Comparação entre a administração central (intratecal) e periférica (gânglio da raiz dorsal) em modelos de dor e hiperalgesia em ratosStudy of analgesia induced by administration of NMDA receptor antagonist - Comparison between central (intrathecal) and peripheral (dorsal root ganglion) administration in pain and hyperalgesia models in rats
(Universidade Federal de UberlândiaBrasilPrograma de Pós-graduação em Ciências da Saúde, 2019)
O bloqueio dos receptores NMDA ou CRF1 no núcleo intersticial da estria terminal impede a ansiogênese induzida pela ativação nitrérgica do córtex pré-frontal medial e derrota social em camundongos
(Universidade Federal de São CarlosUFSCarPrograma Interinstitucional de Pós-Graduação em Ciências Fisiológicas - PIPGCFCâmpus São Carlos, 2019-09-20)
Nitric oxide (NO) release in the right medial prefrontal cortex (RmPFC) produces anxiogenesis. In the bed nucleus of the stria terminalis (BNST), a region that receives neuronal projections from the mPFC, NO also provokes ...
Quantum-chemical structure-affinity studies on kynurenic acid derivatives as Gly/NMDA receptor ligands
(John Wiley & Sons, Inc., 1998-09-28)
A quantum-chemical structure]affinity relationship for kynurenic acid
derivatives KA. acting at the GlyrNMDA site is presented. The results of this study
strongly suggest that these molecules bind to this site through ...
Papel dos receptores glutamatérgicos ionotrópicos do hipotálamo dorsomedial na regulação das respostas cardiovasculares e comportamental do quimiorreflexo
(Universidade Federal de Minas GeraisUFMG, 2012-07-10)
Studies from our laboratory (Queiroz et al., 2011) showed that bilateral microinjection of lidocaine into the DMH reduces the pressor response to chemoreflex. These studies also showed that the bilateral blockade of glutamate ...
Anxiety-like responses induced by nitric oxide within the BNST in mice: Role of CRF1 and NMDA receptors
(Elsevier B.V., 2016-03-01)
It has been shown that the bed nucleus of the stria terminalis (BNST) of rats contains nitrergic neurons, which are activated during animal exposure to aversive stimuli. The BNST is also populated by glutamatergic and ...
Effects of selective NMDA and non-NMDA blockade in the nucleus accumbens on the plus-maze test
(Pergamon-Elsevier Science Ltd, 2002-06)
Effect of blocking N-methyl-D-aspartic acid (NMDA) and non-NMDA-glutamatergic receptors on performance in the plus-maze was studied in male rats bilaterally cannulated into the nucleus accumbens (Acc). Rats were divided ...
Role of nitric oxide in the periaqueductal gray in defensive behavior in mice: influence of prior local N-methyl-D-aspartate receptor activation and aversive condition
(Pontifícia Universidade Católica do Rio de Janeiro (PUC-Rio)Universidade de Brasília (UnB)Universidade de São Paulo (USP), 2010-06-01)
Glutamate N-methyl-D-aspartate (NMDA) receptor activation within the dorsal column of the periaqueductal gray (dPAG) leads to antinociceptive, autonomic, and behavioral responses characterized as the fear reaction. Activation ...
Role of nitric oxide in the periaqueductal gray in defensive behavior in mice: influence of prior local N-methyl-D-aspartate receptor activation and aversive condition
(Pontifícia Universidade Católica do Rio de Janeiro (PUC-Rio)Universidade de Brasília (UnB)Universidade de São Paulo (USP), 2010-06-01)
Glutamate N-methyl-D-aspartate (NMDA) receptor activation within the dorsal column of the periaqueductal gray (dPAG) leads to antinociceptive, autonomic, and behavioral responses characterized as the fear reaction. Activation ...
Role of nitric oxide in the periaqueductal gray in defensive behavior in mice: Influence of prior local N- methyl-D-aspartate receptor activation and aversive condition
(2010-01-01)
Glutamate N-methyl-D-aspartate (NMDA) receptor activation within the dorsal column of the periaqueductal gray (dPAG) leads to antinociceptive, autonomic, and behavioral responses characterized as the fear reaction. Activation ...