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Estudo in silico da interação da protease NS3-NS2B de diferentes Flavivirus com um inibidor peptídico
(BrasilUFRNPROGRAMA DE PÓS-GRADUAÇÃO EM BIOQUÍMICA, 2018-08-08)
Flaviviridae is a large family of viral pathogens responsible for various diseases
and high mortalities worldwide. Dengue (DV), Zika (ZV), West Nile Virus (WNV),
Yellow Fever (YF), Hepatitis C (HC) and Japanese Encephalitis ...
Monomeric nature of dengue virus NS3 helicase and thermodynamic analysis of the interaction with single-stranded RNA
(Oxford University Press, 2014-10)
Dengue virus nonstructural protein 3 (NS3) is a multifunctional protein formed by a superfamily-2 RNA helicase linked to a protease domain. In this work, we report results from in vitro experiments designed to determine ...
The Non-Structural NS1 Protein Unique to Respiratory Syncytial Virus: A Two-State Folding Monomer in Quasi-Equilibrium with a Stable Spherical Oligome
(Public Library Science, 2013-09-10)
Human respiratory syncytial virus (hRSV) is a major infectious agent that cause pediatric respiratory disease worldwide. Considered one of the main virulence factors of hRSV, NS1 is known to suppress type I interferon ...
Production of recombinant NS1 protein and its possible use in encephalitic flavivirus differential diagnosis
(Elsevier Inc, 2019-08-17)
Saint Louis encephalitis virus (SLEV) and West Nile virus (WNV) are two of the major causes of arboviral encephalitis in the Americas. The co-circulation of related flaviviruses in the Americas and prior vaccination against ...
Prognosis and diagnosis of sulfur status in maize by plant analysis
(Elsevier Science, 2019-08)
The analysis of sulfur concentration (S C )and nitrogen to S ratio (N/S)in plant tissue are some of the suggested tools to evaluate S deficiency in maize (Zea mays L.). However, the convenience of one over the other and ...
Specific Mutations in the PB2 Protein of Influenza A Virus Compensate for the Lack of Efficient Interferon Antagonism of the NS1 Protein of Bat Influenza A-Like Viruses
(2018-03-14)
Recently, two new influenza A-like viruses have been discovered in bats, A/little yellow-shouldered bat/Guatemala/060/2010 (HL17NL10) and A/flat-faced bat/Peru/033/2010 (HL18NL11). The hemagglutinin (HA)-like (HL) and ...
Specific Mutations in the PB2 Protein of Influenza A Virus Compensate for the Lack of Efficient Interferon Antagonism of the NS1 Protein of Bat Influenza A-Like Viruses
(2018-03-14)
Recently, two new influenza A-like viruses have been discovered in bats, A/little yellow-shouldered bat/Guatemala/060/2010 (HL17NL10) and A/flat-faced bat/Peru/033/2010 (HL18NL11). The hemagglutinin (HA)-like (HL) and ...