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The antimicrobial peptide Polybia-MP1 differentiates membranes with the hopanoid, diplopterol from those with cholesterol
(2021-01-01)
Polybia-MP1 is an antimicrobial peptide that shows a decreased activity in membranes with cholesterol (CHO). Since it is now accepted that hopanoids act as sterol-surrogates in some sterol-lacking bacteria, we here inquire ...
Salt pumping by voltage-gated nanochannels
(American Chemical Society, 2015-08)
This Letter investigates voltage-gated nanochannels, where both the potential applied to the conductive membrane containing the channel (membrane potential) and the potential difference between the solutions at both sides ...
Carnosic acid is an efflux pumps modulator by dissipation of the membrane potential in Enterococcus faecalis and Staphylococcus aureus
(Springer, 2013-01)
Bacterial resistance to antibiotics has become a serious problem of public health. Along with the controlled permeability by the cell-wall, active efflux systems can provide resistance by extruding antibiotics. Carnosic ...
GABAA receptor and cell membrane potential as functional endpoints in cultured neurons to evaluate chemicals for human acute toxicity
(Pergamon-Elsevier Science Ltd, 2010-02)
Toxicity risk assessment for chemical-induced human health hazards relies mainly on data obtained from animal experimentation, human studies and epidemiology. In vitro testing for acute toxicity based on cytotoxicity assays ...
Efficient Removal of Heavy Metals from Aqueous Solutions through Functionalized γ-Graphyne-1 Membranes under External Uniform Electric Fields: Insights from Molecular Dynamics Simulations.
(American Chemical Society, 2021)
Carbon-based nanosheet membranes with functionalized pores have great potential as water treatment membranes. In this study, the separation of Hg(2+) and Cu(2+) as heavy metal ions from aqueous solutions using a functionalized ...
Computational model for membrane transporters: Potential implications for cancer
(Frontiers Media, 2021-02-22)
To explain the increased transport of nutrients and metabolites and to control the movement of drug molecules through the transporters to the cancer cells, it is important to understand the exact mechanism of their structure ...
Motility and viability of ram sperm cryopreserved in a Tris-egg yolk extender supplemented with anti-oxidants
(Elsevier B.V., 2009-08-01)
The objective of this study was to evaluate the effects of the addition of the anti-oxidants Trolox and catalase to a ram semen cryopreservation extender, on the basis of post-thaw sperm motility, plasma membrane integrity, ...
New findings on Simalikalactone D, an antimalarial compound from Quassia amara L. (Simaroubaceae)
(Elsevier, 2012)
Quassia amara L. (Simaroubaceae) is a species widely used as tonic and is claimed to be an efficient antimalarial all over the Northern part of the Amazon basin. Quassinoid compound Simalikalactone D (SkD) has been shown ...
Separation of potassium clavulanate and potassium chloride by nanofiltration Transport and evaluation of membranes
(Elsevier Science BvAmsterdamHolanda, 2011)