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Identifcation of candidate miRNAs in early‑onset and late‑onset prostate cancer by network analysis
(Nature Publishing GroupReino Unido, 2020)
The incidence of patients under 55 years old diagnosed with Prostate Cancer (EO-PCa) has increased
during recent years. The molecular biology of PCa cancer in this group of patients remains unclear.
Here, we applied ...
Analysis of UV-B regulated miRNAs and their targets in maize leaves
(Landes Bioscience, 2013-10)
UV-B radiation elicits physiological and developmental changes in plants. In this work, to characterize the mechanisms of gene regulation by UV-B radiation, the global miRNA expression profiles in juvenile maize leaves ...
miRNA landscape in pathogenesis and treatment of vogt–koyanagi–harada disease
(Frontiers Media, 2021)
miRNAs, one of the members of the noncoding RNA family, are regulators of gene expression in inflammatory and autoimmune diseases. Changes in miRNA pool expression have been associated with differentiation of CD4(+) T cells ...
beta-ionone modulates the expression of miRNAs and genes involved in the metastatic phenotype of microdissected persistent preneoplastic lesions in rats submitted to hepatocarcinogenesis
(Wiley-Blackwell, 2017-01-01)
MicroRNAs (miRNAs) are post-transcriptional gene expression regulators which expression is frequently altered in hepatocellular carcinoma (HCC). -ionone (I) is noted for its ability to inhibit persistent preneoplastic ...
Keep calm and carry on: miRNA biogenesis under stress
(Wiley Blackwell Publishing, Inc, 2019-06)
MicroRNAs (miRNAs) are major post-transcriptional regulators of gene expression. Their biogenesis relies on the cleavage of longer precursors by a nuclear localized processing machinery. The evolutionary preference of plant ...
LncRNA HOTAIR is a novel endothelial mechanosensitive gene
(2020-05-01)
To better address whether the long noncoding RNAs (lncRNAs) HOTAIR and HOTTIP are mechanosensitive genes, they were investigated in differentially challenged endothelial cells with respect to a circuit of tensional forces, ...
MicroRNA roles in regeneration: Multiple lessons from zebrafish
(2022-04-01)
MicroRNAs (miRNAs) are small noncoding RNAs with pivotal roles in the control of gene expression. By comparing the miRNA profiles of uninjured vs. regenerating tissues and structures, several studies have found that miRNAs ...
MicroRNAs in Taenia solium Neurocysticercosis: Insights as Promising Agents in Host-Parasite Interaction and Their Potential as Biomarkers
(Frontiers Media, 2017)
MicroRNAs (miRNAs) are short, endogenous, non-coding, single-stranded RNAs involved in post-transcriptional gene regulation. Although, several miRNAs have been identified in parasitic helminths, there is little information ...
miRNA let-7b inhibitors by treatment of diabetic retinopathy: evaluation patent US2019093106
(Benemérita Universidad Autónoma de Puebla, 2020-05-21)
Introduction: diabetic retinopathy is a clinical complication that affects to a 93 million people suffering from diabetes and is responsible for more hospitalizations than any other complication of diabetes. Authors of ...