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Chemopreventive effects of beta-ionone and geraniol during rat hepatocarcinogenesis promotion: distinct actions on cell proliferation, apoptosis, HMGCoA reductase, and RhoA
(ELSEVIER SCIENCE INC, 2011)
Chemopreventive activities of the dietary isoprenoids beta-ionone (beta I) and geraniol (GOH) were evaluated during the promotion phase of hepatocarcinogenesis. Over 5 consecutive weeks, rats received daily 16 mg/100 g ...
Synergistic activity between statins and bisphosphonates against acute experimental toxoplasmosis
(American Society for Microbiology, 2017-08)
Bisphosphonates are widely used for the treatment of bone disorders. These drugs also inhibit the growth of a variety of protozoan parasites, such as Toxoplasma gondii, the etiologic agent of toxoplasmosis. The target of ...
Síntese e avaliação farmacológica de lactonas de 14 - membros planejadas a partir dos lipídeos fenólicos não - isoprenóides de anacardium occidentale
(2008-08)
O liquido da casca da castanha (LCC) é uma importante fonte de lipídios fenólicos não isoprenóides, por exemplo, os ácidos anacárdicos, cardóis, cardanóis e metil cardóis. Devido apresentarem caráter aromático e acíclico ...
Phytochrome-dependent Temperature Perception Modulates Isoprenoid Metabolism
(American Society of Plant Biologist, 2020-05)
Changes in environmental temperature influence many aspects of plant metabolism; however, the underlying regulatory mechanisms remain poorly understood. In addition to their role in light perception, phytochromes (PHYs) ...
A role for β,β-xanthophylls in Arabidopsis UV-B photoprotection
(Oxford University Press, 2018-09)
Plastidial isoprenoids, such as carotenoids and tocopherols, are important anti-oxidant metabolites synthesized in plastids from precursors generated by the methylerythritol 4-phosphate (MEP) pathway. In this study, we ...
Sterol regulatory element-binding protein Sre1 regulates carotenogenesis in the red yeast Xanthophyllomyces dendrorhous
(Amer Soc Biochemistry Molecular Biology, 2020)
Xanthophyllomyces dendrorhous is a basidiomycete
yeast that produces carotenoids, mainly astaxanthin. Astaxanthin
is an organic pigment of commercial interest due to
its antioxidant and coloring properties. X. dendrorhous ...
Metallopeptidase Stp1 activates the transcription factor Sre1 in the carotenogenic yeast Xanthophyllomyces dendrorhous
(American Society for Biochemistry and Molecular Biology, 2020)
Xanthophyllomyces dendrorhous is a basidiomycete yeast known as a natural producer of astaxanthin, a carotenoid of commercial interest because of its antioxidant properties. Recent studies indicated that X. dendrorhous has ...