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Carbohydrate- and lipid-enriched meals acutely disrupt glycemic homeostasis by inducing transient insulin resistance in rats
(CANADIAN SCIENCE PUBLISHING, NRC RESEARCH PRESSOTTAWA, 2012)
Chronic intake of high-carbohydrate or high-lipid diets is a well-known insulin resistance inducer. This study investigates the immediate effect (1-6 h) of a carbohydrate-or lipid-enriched meal on insulin sensitivity. ...
Antioxidant and anti-inflammatory properties of gamma- oryzanol attenuates insulin resistance by increasing GLUT- 4 expression in skeletal muscle of obese animals
(2021-11-01)
Background: Skeletal muscle is the most important organ for whole-body glucose homeostasis. However, it has been suggested that obesity-related inflammation could be involved in insulin resistance and diabetes mellitus ...
Insulin signaling proteins in pancreatic islets of insulin-resistant rats induced by glucocorticoid
(Soc Biolgia ChileSantiagoChile, 2011)
Atorvastatin and diacerein reduce insulin resistance and increase disease tolerance in rats with sepsis
(2018-05-09)
Background: Sepsis is one of the leading causes of death among hospitalized patients. At the onset of this condition, there is an over-production of pro-inflammatory mediators that contribute to organ failure and death. ...
Microbiota determines insulin sensitivity in TLR2-KO mice
(2019-10-01)
Introduction: Environmental factors have a key role in the control of gut microbiota and obesity. TLR2 knockout (TLR2−/−) mice in some housing conditions are protected from diet-induced insulin resistance. However, in our ...
Protein deficiency and nutritional recovery modulate insulin secretion and the early steps of insulin action in rats
(Amer Inst NutritionBethesdaEUA, 1998)
Functional alterations in endocrine pancreas of rats with different degrees of dexamethasone-induced insulin resistance
(Lippincott Williams & Wilkins, 2008-04-01)
Objectives: We have analyzed the peripheral insulin and glucose sensitivity in vivo, and islet function ex vivo in rats with different degrees of insulin resistance induced by dexamethasone (DEX).Methods: Dexamethasone, ...