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Dendritic cells from X-linked hyper-IgM patients present impaired responses to Candida albicans and Paracoccidioides brasiliensis
(MOSBY-ELSEVIERNEW YORK, 2012)
Background: Patients with X-linked hyper-IgM syndrome (X-HIGM) due to CD40 ligand (CD40L) mutations are susceptible to fungal pathogens; however, the underlying susceptibility mechanisms remain poorly understood. Objective: ...
Dendritic cells from X-linked hyper-IgM patients present impaired responses to Candida albicans and Paracoccidioides brasiliensis
(Elsevier B.V., 2012-03-01)
Background: Patients with X-linked hyper-IgM syndrome (X-HIGM) due to CD40 ligand (CD40L) mutations are susceptible to fungal pathogens; however, the underlying susceptibility mechanisms remain poorly understood.Objective: ...
Clinical and Virologic Outcomes after Changes in First Antiretroviral Regimen at 7 Sites in the Caribbean, Central and South America Network
(Wolters Kluwer Health, 2016)
Background: HIV-infected persons in resource-limited settings may experience high rates of antiretroviral therapy (ART) change, particularly because of toxicity or other nonfailure reasons. Few reports address patient ...
Doctors' awareness concerning primary immunodeficiencies in Brazil
(Elsevier B.V., 2015-05-01)
Background: PIDs are a heterogeneous group of genetic illnesses, and delay in their diagnosis is thought to be caused by a lack of awareness among physicians concerning PIDs. the latter is what we aimed to evaluate in ...
Understanding systemic lupus erythematosus physiopathology in the light of primary immunodeficiencies
(SPRINGER/PLENUM PUBLISHERS, 2008)
Introduction Associations between systemic lupus erythematosus (SLE) and primary immunodeficiencies (PIDs) were analyzed to gain insight into the physiopathology of SLE. Some PIDs have been consistently associated with SLE ...
Efeitos do treinamento muscular inspiratório na função pulmonar de pacientes com Ataxia Telangiectasia
(Universidade Federal de São Paulo (UNIFESP), 2011-03-30)
Background: Ataxia Telangiectasia (A-T) is an autosomal recessive syndrome, characterized by defects in DNA repair or replication which is caused by a mutation in a gene on the chromosome 11. The typical manifestations are ...
Incidence of virological failure and major regimen change of initial combination antiretroviral therapy in the Latin America and the Caribbean: An observational cohort study
(Elsevier, 2015)
Background: Access to combination antiretroviral therapy (ART) is expanding in Latin America (Mexico, Central America, and South America) and the Caribbean. We assessed the incidence of and factors associated with regimen ...
Mortality and loss to follow-up among HIV-infected persons on long-term antiretroviral therapy in Latin America and the Caribbean
(Wiley, 2015)
Introduction: Long-term survival of HIV patients after initiating highly active antiretroviral therapy (ART) has not been sufficiently described in Latin America and the Caribbean, as compared to other regions. The aim of ...
The Extended Clinical Phenotype of 26 Patients with Chronic Mucocutaneous Candidiasis due to Gain-of-Function Mutations in STAT1
(SpringerInmunodeficiencias PrimariasNueva York, Estados Unidos, 2023)