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Regulation of liver glucokinase activity in rats with fructose-induced insulin resistance and impaired glucose and lipid metabolism
(National Research Council Canada-NRC Research Press, 2009-09)
We evaluated the relative role of different regulatory mechanisms, particularly 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase (PFK2/FBPase-2), in liver glucokinase (GK) activity in intact animals with fructose-induced ...
Bifunctional ADP-dependent phosphofructokinase/ glucokinase activity in the order Methanococcales – biochemical characterization of the mesophilic enzyme from Methanococcus maripaludis
(FEBS, 2014)
In some archaea, the phosphorylation of glucose and fructose 6-phosphate
(fructose 6P) is carried out by enzymes that are specific for either substrate
and that use ADP as phosphoryl donor. In the hyperthermophilic ...
Pyridoxine dipharmacophore derivatives as potent glucokinase activators for the treatment of type 2 diabetes mellitus
(Nature Publishing Group, 2017)
Single molecule studies by optical tweezers: folding and unfolding of glucokinase from Thermococcus litoralis
(Universidad de Chile, 2011)
En esta tesis utilizamos la técnica de pinzas opticas para investigar el efecto que
ejerce el sustrato sobre la estabilidad mecánica de la enzima glucoquinasa de la arquea
hipertermofila Thermococcus litoralis que crece ...