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Aminoglycoside-resistance gene signatures are predictive of aminoglycoside MICs for carbapenem-resistant Klebsiella pneumoniae
(Oxford University Press, 2022)
Background: Aminoglycoside-containing regimens may be an effective treatment option for infections caused by carbapenem-resistant Klebsiella pneumoniae (CR-Kp), but aminoglycoside-resistance genes are common in these ...
Aminoglycoside-resistance gene signatures are predictive of aminoglycoside MICs for carbapenem-resistant Klebsiella pneumoniae.
(Oxford University Press, 2022)
BACKGROUND: Aminoglycoside-containing regimens may be an effective treatment option for infections caused by carbapenem-resistant Klebsiella pneumoniae (CR-Kp), but aminoglycoside-resistance genes are common in these ...
Cross-platform comparison of independent datasets identifies an immune signature associated with improved survival in metastatic melanoma
(Impact Journals, 2016-02)
Platform and study differences in prognostic signatures from metastatic melanoma (MM) gene expression reports often hinder consensus arrival. We performed survival/outcome-based pairwise comparisons of three independent ...
Applications in the search for genomic selection signatures in fish
(Frontiers Media S.A., 2014)
© 2014 Lopez_dinamarca, Neira and Yáñez. Selection signatures are genomic regions harboring DNA sequences functionally involved in the genetic variation of traits subject to selection. Selection signatures have been ...
Prospection of genomic regions divergently selected in cutting line of quarter horses in relation to racing line
(Elsevier B.V., 2015-04-01)
The objective of this study was to identify genomic regions divergently selected in the cutting line of Quarter Horses in relation to the racing line using SNP genotyping arrays and the relative extended haplotype homozygosity ...
A machine learning approach to predict gene expression signatures, local gene networks, and key genes for biological functions of interest.
(2015)
Un objetivo importante en la investigación biológica es descubrir genes relevantes para funciones biológicas de interés. Estas funciones pueden tener distintos grados de complejidad, desde procesos biológicos específicos ...
A novel gene signature unveils three distinct immune-metabolic rewiring patterns conserved across diverse tumor types and associated with outcomes
(Frontiers Media, 2022)
Existing immune signatures and tumor mutational burden have only modest predictive capacity for the efficacy of immune check point inhibitors. In this study, we developed an immune-metabolic signature suitable for personalized ...
Gene signatures induced by ionizing radiation as prognostic tools in an in vitro experimental breast cancer model
(MDPI, 2021)
Simple Summary The present work analyzed the expression of genes involved in radiation, using an in vitro experimental breast cancer model developed by the combined treatment of low doses of high linear energy transfer ...
Assessing signatures of selection through variation in linkage disequilibrium between taurine and indicine cattle
(Biomed Central Ltd., 2014-03-04)
Background: Signatures of selection are regions in the genome that have been preferentially increased in frequency and fixed in a population because of their functional importance in specific processes. These regions can ...