Buscar
Mostrando ítems 51-60 de 7024
Drug delivery systems: Past, present, and future
(Bentham Science Publ Ltd, 2004-07-01)
Drug delivery systems are essential components of drugs controlled release. In the last decades, several drug delivery technologies have emerged including capsules, liposomes. microparticles, nanoparticles, and polymers. ...
Drug delivery systems: Past, present, and future
(Bentham Science Publ Ltd, 2004-07-01)
Drug delivery systems are essential components of drugs controlled release. In the last decades, several drug delivery technologies have emerged including capsules, liposomes. microparticles, nanoparticles, and polymers. ...
Target-Pathogen: A structural bioinformatic approach to prioritize drug targets in pathogens
(Oxford University Press, 2018-01)
Available genomic data for pathogens has created new opportunities for drug discovery and development to fight them, including new resistant and multiresistant strains. In particular structural data must be integrated with ...
Paromomycin: a potential dual targeted drug effectively inhibits both Spike (S1) and Main Protease of COVID-19
Objectives: With increase in number of people suffering from COVID-19, there is a dire need to
look for effective remedies against this pandemic. Drug repurposing seems to be the solution for
current situation.
Methods: ...
Nanosystem functionalization strategies for prostate cancer treatment: a review
(2021-01-01)
Prostate cancer (PC) has a high morbidity and mortality rate worldwide, and the current clinical guidelines can vary depending on the stage of the disease. Drug delivery nanosystems (DDNs) can improve biopharmaceutical ...
Alzheimer's disease: Related targets, synthesis of available drugs, bioac-tive compounds under development and promising results obtained from multi-target approaches
(2021-01-01)
We describe herein the therapeutic targets involved in Alzheimer’s disease as well as the available drugs and their synthetic routes. Bioactive compounds under development are also exploited to illustrate some recent ...
MRSA infections: from classical treatment to suicide drugs
(Bentham Science Publishers, 2014-02)
Infections caused by the methicillin-resistant Staphylococcus aureus (MRSA) are today a major burden in nosocomial disease control. The global trend shows an alarming increase of MRSA infections as well as multi-drug ...
The Thiol-polyamine Metabolism of Trypanosoma cruzi: Molecular Targets and Drug Repurposing Strategies
(Bentham Science Publishers, 2018-09)
Chagas´ disease continues to be a challenging and neglected public health problem in many American countries. The etiologic agent, Trypanosoma cruzi, develops intracellularly in the mammalian host, which hinders treatment ...
How Can Network-Pharmacology Contribute to Antiepileptic Drug Development?
(Smart Science & Technology, 2014-02)
Network-pharmacology is a field of pharmacology emerging from the observation that most clinical drugs have multiple targets, contrasting with the previously dominant magic bullet paradigm which proposed the search of ...