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Beta2-adrenergic receptor regulates cardiac fibroblast autophagy and collagen degradation
(2011)
Autophagy is a physiological degradative process key to cell survival during nutrient deprivation, cell differentiation and development. It plays a major role in the turnover of damaged macromolecules and organelles, and ...
Heparan sulfate potentiates leukocyte adhesion on cardiac fibroblast by enhancing Vcam-1 and Icam-1 expression
(Elsevier, 2018)
Cardiac fibroblasts (CF) act as sentinel cells responding to chemokines, cytokines and growth factors released in cardiac tissue in cardiac injury events, such as myocardial infarction (MI). Cardiac injury involves the ...
Decreased Nitric Oxide Products in the Urine of Patients Undergoing Cardiac Surgery
(W B SAUNDERS CO-ELSEVIER INC, 2009)
Objective: Renal vasoconstriction has been blamed as a cause of perioperative renal dysfunction after cardiac surgery. Endothelial function is a critical determinant of vascular tonus, including vasoconstriction. The ...
Toxic mechanism of cadmium exposure on cardiac tissue
(2000-12-01)
The presence of toxic substances in the workplace environment requires systematic evaluation of exposure and health status in exposed subjects. Cadmium is a highly toxic element found in water. Although free mediated ...
Toxic mechanism of cadmium exposure on cardiac tissue
(2000-12-01)
The presence of toxic substances in the workplace environment requires systematic evaluation of exposure and health status in exposed subjects. Cadmium is a highly toxic element found in water. Although free mediated ...
Unbalance between sarcoplasmic reticulum Ca2 + uptake and release: A first step toward Ca2 + triggered arrhythmias and cardiac damage
(Frontiers Media, 2020-01-23)
The present review focusses on the regulation and interplay of cardiac SR Ca2+ handling proteins involved in SR Ca2+ uptake and release, i.e., SERCa2/PLN and RyR2. Both RyR2 and SERCA2a/PLN are highly regulated by ...
Galectin-1 Prevents Infection and Damage Induced by Trypanosoma cruzi on Cardiac Cells
(Public Library of Science, 2015-10-09)
Chronic Chagas cardiomyopathy caused by Trypanosoma cruzi is the result of a pathologic process starting during the acute phase of parasite infection. Among different factors, the specific recognition of glycan structures ...
Expression and function of toll-like receptor 4 and inflammasomes in cardiac fibroblasts and myofibroblasts: IL-1 beta synthesis, secretion, and degradation
(Elsevier, 2016)
Cardiac inflammation can be produced by pathogen-associated molecular patterns (PAMPs), from parasitic, bacterial or viral origin; or by danger-associated molecular patterns (DAMPs), released from dead cells after cardiac ...
Changes in hemodynamic and neurohumoral control cause cardiac damage in one-kidney, one-clip hypertensive mice
(AMER PHYSIOLOGICAL SOC, 2008)
Borges GR, Salgado HC, Silva CA, Rossi MA, Prado CM, Fazan R Jr. Changes in hemodynamic and neurohumoral control cause cardiac damage in one-kidney, one-clip hypertensive mice. Am J Physiol Regul Integr Comp Physiol 295: ...