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Uso da modelagem molecular na solução de problemas em química
(Universidade Federal de São CarlosBRUFSCarPrograma de Pós-Graduação em Química - PPGQ, 2014-08-29)
The studies presented herein show the use of molecular modelling coupled to spectroscopic data to tackle four different problems in organic chemistry. In the first study, the sulfonylation of the primary hydroxyl group of ...
Phosphonate mesoporous hybrid thin films: Synthesis of organophosphosilane by thiol-ene click chemistry and applications in formation and stabilization of silver nanoparticles
(Elsevier Science, 2020-03)
The synthesis of hybrid inorganic organic mesoporous films with pores displaying phosphonic acid functions and their use as template for Ag nanoparticles are presented here. The Photochemical radical thiol – ene addition ...
'Click chemistry' synthesis of a library of 1,2,3-triazole-substituted galactose derivatives and their evaluation against Trypanosoma cruzi and its cell surface trans-sialidase
(Elsevier B.V., 2010-04-01)
Trypanosoma cruzi trans-sialidase (TcTS) plays a key role in the recognition and invasion of host cells and in enabling the parasite to escape the human immune response. To explore this potential drug target, we have ...
An Optimized Protocol for the Synthesis of Peptides Containing trans-Cyclooctene and Bicyclononyne Dienophiles as Useful Multifunctional Bioorthogonal Probes
(Wiley VCH Verlag, 2021-09-09)
Despite the great advances in solid-phase peptide synthesis (SPPS), the incorporation of certain functional groups into peptide sequences is restricted by the compatibility of the building blocks with conditions used during ...
Click chemistry of multi-walled carbon nanotubes-G-1,3-diazido-2-isopropanol with alkyne groups
(Advanced Study Center Co. Ltd., 2017)
The click chemistry was employed on oxidized multiwall carbon nanotubes for their
functionalization with 1,3-diazido-2-isopropanol (2N3OH). Phenylacetylene and propargylamine
are used as alkyne groups, catalyzed with ...