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High chromosomal instability in workers occupationally exposed to solvents and paint removers
(2016)
Background: Painters are exposed to an extensive variety of harmful substances like aromatic hydrocarbons used as solvents and paint removers, some of which have shown clastogenic activity. These substances constitute a ...
Chromosome polymorphism in the Brazilian dwarf brocket deer, Mazama nana (Mammalia, Cervidae)
(Sociedade Brasileira de Genética, 2008-01-01)
The Brazilian dwarf brocket deer (Mazama nana) is the smallest deer species in Brazil and is considered threatened due to the reduction and alteration of its habitat, the Atlantic Rainforest. Moreover, previous work suggested ...
Chromosome polymorphism in the Brazilian dwarf brocket deer, Mazama nana (Mammalia, Cervidae)
(Sociedade Brasileira de Genética, 2008-01-01)
The Brazilian dwarf brocket deer (Mazama nana) is the smallest deer species in Brazil and is considered threatened due to the reduction and alteration of its habitat, the Atlantic Rainforest. Moreover, previous work suggested ...
Genetic instability induced by low doses of x-rays in hamster cells
(Taylor & Francis Ltd, 2007-12)
Purpose: Genomic instability involves time delayed events and can be manifested as elevated rates of heritable changes in the progeny of irradiated cells. To study the induction of chromosomal instability by very low doses ...
The role of chromosomal instability in cancer and therapeutic responses
(2018)
Cancer is one of the leading causes of death, and despite increased research in recent years, control of advanced-stage disease and optimal therapeutic responses remain elusive. Recent technological improvements have ...
Chromosomal Instability in Mouse Embryonic Fibroblasts Null for the Transcriptional Co-Repressor Ski
(WILEY-BLACKWELL, 2012-01)
Ski is a transcriptional regulator that has been considered an oncoprotein given its ability to induce oncogenic transformation in avian model systems. However, studies in mouse and in some human tumor cells have also ...
Genetic alterations in benign lesions: Chronic gastritis and gastric ulcer
(2006-01-28)
Aim: To investigate the occurrence of chromosome 3, 7, 8, 9, and 17 aneuploidies, TP53 gene deletion and p53 protein expression in chronic gastritis, atrophic gastritis and gastric ulcer, and their association with H pylori ...
Genetic alterations in benign lesions: Chronic gastritis and gastric ulcer
(2006-01-28)
Aim: To investigate the occurrence of chromosome 3, 7, 8, 9, and 17 aneuploidies, TP53 gene deletion and p53 protein expression in chronic gastritis, atrophic gastritis and gastric ulcer, and their association with H pylori ...
High frequencies of telomeric associations, chromosome aberrations, and sister chromatid exchanges in ulcerative colitis
(Nature Publishing Group, 2000-09)
Chromosome instability provides a predisposing background to malignancy, contributing to the crucial genetic changes in multistep carcinogenesis. The aim of this work was to analyze chromosome instability in patients with ...