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Cdk5 regulates Rap1 activity
(2013)
Rap1 signaling is important for migration, differentiation, axonal growth, and during neuronal polarity. Rap1 can be activated by external stimuli, which in turn regulates specific guanine nucleotide exchange factors such ...
Molecular model of cyclin-dependent kinase 5 complexed with roscovitine
(Elsevier B.V., 2014)
Molecular models of cyclin-dependent kinase 1 complexed with inhibitors
(Elsevier B.V., 2014)
Structural Basis for Interaction of Inhibitors with Cyclin-Dependent Kinase 2
(Bentham Science Publ Ltd, 2005-01-01)
Cell cycle progression is tightly controlled by the activity of cyclin-dependent kinases (CDKs). CDKs are inactive as monomers, and activation requires binding to cyclins, a diverse family of proteins whose levels oscillate ...
Structural Basis for Interaction of Inhibitors with Cyclin-Dependent Kinase 2
(Bentham Science Publ Ltd, 2005-01-01)
Cell cycle progression is tightly controlled by the activity of cyclin-dependent kinases (CDKs). CDKs are inactive as monomers, and activation requires binding to cyclins, a diverse family of proteins whose levels oscillate ...
Searching for novel Cdk5 substrates in brain by comparative phosphoproteomics of wild type and Cdk5-/- mice
(Public Library of Science, 2014)
Protein phosphorylation is the most common post-translational modification that regulates several pivotal functions in cells. Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase which is mostly ...
Regulación de la expresión de receptores de glicina mediada por la activación o inhibición de la proteína quinasa dependiente de ciclina 5 (Cdk5)
(Universidad de Concepción, 2023)
La quinasa dependiente de ciclina 5 (Cdk5) es una enzima que fosforila residuos de serina o treonina dirigidos por prolina. Cdk5 participa en diferentes etapas del desarrollo del sistema nervioso y está mayoritariamente ...