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Characterization of Brown spider (Loxosceles intermedia) hemolymph: Cellular and biochemical analyses
(Elsevier B.V., 2015-05-01)
This is the first study on the hemolymph from a spider of the Loxosceles genus. These animals are responsible for a great number of envenomation cases worldwide. Several studies on Loxosceles venoms have been published, ...
Active site mapping of Loxosceles phospholipases D: Biochemical and biological features
(Elsevier Science Bv, 2016)
Brown spider phospholipases D from Loxosceles venoms are among the most widely studied toxins since they induce dermonecrosis, triggering inflammatory responses, increase vascular permeability, cause hemolysis, and renal ...
Active site mapping of Loxosceles phospholipases D: Biochemical and biological features
(2016-09-01)
Brown spider phospholipases D from Loxosceles venoms are among the most widely studied toxins since they induce dermonecrosis, triggering inflammatory responses, increase vascular permeability, cause hemolysis, and renal ...
Structural insights into substrate binding of brown spider venom class ii phospholipases d
(2015-09-01)
Phospholipases D (PLDs), the major dermonecrotic factors from brown spider venoms, trigger a range of biological reactions both in vitro and in vivo. Despite their clinical relevance in loxoscelism, structural data is ...
Análise do transcriptoma da glândula produtora de veneno de Loxosceles intermedia (aranha marrom): perfil de expressão e identificação de novas toxinas
(Universidade Federal de São Paulo (UNIFESP), 2010-07-28)
Loxosceles genus spiders are responsible for accidents all over the world and have clinical importance in the South of Brazil. The venom of these spiders is made up of several toxins, including proteins, which are responsible ...
Biological and structural comparison of recombinant phospholipase D toxins from Loxosceles intermedia (brown spider) venom
(Elsevier B.V., 2007-12-15)
The clinical features of brown spider bites are the appearance of necrotic skin lesions, which can also be accompanied by systemic involvement, including weakness, vomiting, fever, convulsions, disseminated intravascular ...
Two novel dermonecrotic toxins LiRecDT4 and LiRecDT5 from Brown spider (Loxosceles intermedia) venom: From cloning to functional characterization
(Elsevier B.V., 2007-03-01)
Loxoscelism (the condition produced by the bite of brown spiders) has been reported worldwide, but especially in warmer regions. Clinical manifestations include skin necrosis with gravitational spreading while systemic ...
ADULT-OBTAINED PYRROLIZIDINE ALKALOIDS DEFEND ITHOMIINE BUTTERFLIES AGAINST A SPIDER PREDATOR
(Macmillan Magazines LtdLondonInglaterra, 1984)
Structural and ultrastructural description of the venom gland of Loxosceles intermedia (brown spider)
(Elsevier B.V., 2000-02-01)
The brown spider, genus Loxosceles, is becoming of great medical importance, with envenomation (Loxoscelism) occurring throughout the world. the biological activities of the brown spider venom usually include dermonecrotic ...
Effect of venom gland extracts of the South American brown spider, Loxosceles laeta, on in vitro protein synthesis
(1983)
There was no effect of the venom extract on incorporation of phenylalanine into protein from phenylalanyl-tRNA. In contrast, the esterification of amino acids with tRNA was inhibited by the venom extracts in a dose-dependent ...