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Trypomastigote Excretory Secretory Antigen Blot Is Associated with Trypanosoma cruzi Load and Detects Congenital T. cruzi Infection in Neonates, Using Anti-Shed Acute Phase Antigen Immunoglobulin M
(Oxford University Press, 2019)
Background: Congenital Trypanosoma cruzi infection accounts for an estimated 22% of new cases of Chagas disease in Latin America. However, neonatal diagnosis is challenging, as 9-month follow-up for immunoglobulin G testing ...
Anti-parasite activity of novel 3,5-diiodophenethyl-benzimides
(Sociedade Brasileira de QuímicaProductos Naturales MarinosPrograma de Estudio y Control de Enfermedades Tropicales (PECET)São Paulo, Brasil, 2023)
The potential of canine sentinels for reemerging Trypanosoma cruzi transmission
(Elsevier, 2015)
BACKGROUND: Chagas disease, a vector-borne disease transmitted by triatomine bugs and caused by the parasite Trypanosoma cruzi, affects millions of people in the Americas. In Arequipa, Peru, indoor residual insecticide ...
Detection of antibodies to Toxoplasma gondii in wild animals in Brazil
(Centro de Estudos de Venenos e Animais Peçonhentos - CEVAP, Universidade Estadual Paulista - UNESP, 2014)
Background Toxoplasmosis is a worldwide zoonosis caused by an obligate intracellular protozoan parasite, Toxoplasma gondii, that affects all warm-blooded animals, including wild animals. The increased number of cases of ...
Kinetic characterization of a novel cysteine peptidase from the protozoan Babesia bovis, a potential target for drug design
(Elsevier, 2020-12)
C1A cysteine peptidases have been shown to play an important role during apicomplexan invasion and egress of host red blood cells (RBCs) and therefore have been exploited as targets for drug development, in which peptidase ...
In vitro evaluation of a soluble Leishmania promastigote surface antigen as a potential vaccine candidate against human leishmaniasis
(Public Library of Science, 2014)
PSA (Promastigote Surface Antigen) belongs to a family of membrane-bound and secreted proteins present in several Leishmania (L.) species. PSA is recognized by human Th1 cells and provides a high degree of protection in ...
Detecção de anticorpos anti-Leishmania spp. em aves domésticas de Santa Maria-RS, sul do Brasil
(Universidade Federal de Santa MariaBrasilMedicina VeterináriaUFSMPrograma de Pós-Graduação em Medicina VeterináriaCentro de Ciências Rurais, 2023-03-08)
Domestic birds such as chickens (Gallus gallus), turkeys (Meleagris gallopavo) and geese
(Anser anser) are raised extensively, coexisting with humans, domestic and wild animals,
known to be hosts and reservoirs of protozoa ...