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Histological and Functional Organization in Human Testicle: Expression of Receptors c-kit and Androgens
(SOC CHILENA ANATOMIA, 2008-09)
The objective of this work was identify the presence of interstitial cells of Cajal, muscle cells, nerves and androgen
receptor positive cells in adult human testicle, using immunohistochemical detection for c-kit/CD-117, ...
Silencing of the transcriptional factor ZEB1 alters the steroidogenic pathway, and increases the concentration of testosterone and DHT in DU145 cells
(Spandidos Publications, 2019)
© 2019 Spandidos Publications. All rights reserved.Prostate cancer (PCa) is the second most common type of male malignancy worldwide. The transcription factor zinc finger E-box binding homeobox 1 (ZEB1) is associated with ...
Progesterone restores the female prostate activity in ovariectomized gerbil and may act as competitor of testosterone in intraprostatic environment
(2013-05-30)
Aims Little is known about the effect of progesterone on gerbil female prostate. It is known that normal oscillation in the progesterone and estradiol levels during the estrous cycle phases influence the morphophysiology ...
Progesterone restores the female prostate activity in ovariectomized gerbil and may act as competitor of testosterone in intraprostatic environment
(2013-05-30)
Aims Little is known about the effect of progesterone on gerbil female prostate. It is known that normal oscillation in the progesterone and estradiol levels during the estrous cycle phases influence the morphophysiology ...
Neonatal exposure to aluminum chloride disrupts branching morphogenesis and hormonal signaling of the ventral male prostate and female prostate of gerbils
(2020-09-01)
Backgroung: Exposure to environmental pollutants in critical developmental windows may predispose the prostate to permanent changes in its homeostasis. Thus, it is essential to know the effects that environmental toxics, ...
Androgen responsive intronic non-coding RNAs
(2007-01)
Abstract
Background
Transcription of large numbers of non-coding RNAs originating from intronic regions of human genes has ...
Maternal testosterone exposure increases anxiety-like behavior and impacts the limbic system in the offspring
(National Academic Sciences, 2015)
During pregnancy, women with polycystic ovary syndrome (PCOS) display high circulating androgen levels that may affect the fetus and increase the risk of mood disorders in offspring. This study investigated whether maternal ...
Molecular alterations in primary prostate cancer after androgen ablation therapy
(AMER ASSOC CANCER RESEARCH, 2005)
Purpose: After an initial response to androgen ablation, most prostate tumors recur, ultimately progressing to highly aggressive androgen-independent cancer. The molecular mechanisms underlying progression are not well ...
Body composition alterarions, energy expenditure and fat oxidation in elderly males suffering from prostate cancer, pre and post orchiectomy
(Faculdade de Medicina / USP, 2009)
INTRODUCTION: Testosterone is needed for normal male development, muscle strength, bone mineralization, hematopoietic function, and sexual and reproductive functions. The main purpose of androgen deprivation therapy in ...