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Glucose metabolism regulates T cell activation, differentiation, and functions
(Frontiers Research Foundation, 2015-01)
The adaptive immune system is equipped to eliminate both tumors and pathogenic microorganisms. It requires a series of complex and coordinated signals to drive the activation, proliferation, and differentiation of appropriate ...
AKT1 and MYC Induce Distinctive Metabolic Fingerprints in Human Prostate Cancer
(American Association for Cancer Research, 2014-12)
Cancer cells may overcome growth factor dependence by deregulating oncogenic and/or tumor-suppressor pathways that affect their metabolism, or by activating metabolic pathways de novo with targeted mutations in critical ...
Protein Kinase CK2 in Cancer Energetics
(Frontiers Media S.A., 2020-06)
Protein kinase CK2 (formerly known as casein kinase 2) is abnormally elevated in many cancers. This may increase tumor aggressiveness through CK2-dependent phosphorylation of key proteins in several signaling pathways. In ...
Peach (Prunus Persica) Fruit Response to Anoxia: Reversible Ripening Delay and Biochemical Changes
(Oxford Academic Press, 2011-02)
The use of modified atmospheres has been successfully applied in different fruits to delay the ripening process and to prevent physiological disorders. In addition, during normal ripening, hypoxic areas are generated inside ...
Differential Proteomic Analysis of Noncardia Gastric Cancer from Individuals of Northern Brazil
(Public Library Science, 2012-07-30)
Gastric cancer is the second leading cause of cancer-related death worldwide. the identification of new cancer biomarkers is necessary to reduce the mortality rates through the development of new screening assays and early ...
PPARβ/δ-dependent MSC metabolism determines their immunoregulatory properties
(2020-12-01)
Mesenchymal stem cell (MSC)-based therapy is being increasingly considered a powerful opportunity for several disorders based on MSC immunoregulatory properties. Nonetheless, MSC are versatile and plastic cells that require ...
Obtención de BHET a partir de residuos de botellas plásticas de PET mediante glicólisis catalizada con ceniza de cáscara de naranja
(Universidad de los AndesIngeniería QuímicaFacultad de IngenieríaDepartamento de Ingeniería Química y de Alimentos, 2022-09-02)
Uno de los principales problemas ambientales actualmente es el de la contaminación por residuos plásticos y una de las soluciones planteadas es la del reciclaje químico. En el presente proyecto se trabajó la glicólisis ...
Lactato y catecolaminas: respuesta fisiológica en el paciente crítico
(Universidad de San Martín de Porres. Facultad de Medicina Humana, 2022-03-18)
El lactato es un metabolito altamente dinámico que, en condiciones anaerobias, es producido por hipoxia o isquemia; y en
condiciones aerobias, es sintetizado por un mecanismo impulsado por la estimulación adrenérgica, a ...
Myoglobins: the link between discoloration and lipid oxidation in muscle and meat
(Sociedade Brasileira de Química, 2006)