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The Enigmatic Role of C9ORF72 in Autophagy
(FRONTIERS MEDIA SA, 2017-08-03)
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by the loss of motor neurons resulting in a progressive and irreversible muscular paralysis. Advances in large-scale genetics and ...
Apathy, executive function, and emotion recognition are the main drivers of functional impairment in behavioral variant of frontotemporal dementia
(Frontiers Media, 2022)
Background: The cognitive and neuropsychiatric deficits present in patients with behavioral variant frontotemporal dementia (bvFTD) are associated with loss of functionality in the activities of daily living (ADLs). The ...
Apathy, Executive Function, and Emotion Recognition Are the Main Drivers of Functional Impairment in Behavioral Variant of Frontotemporal Dementia
(FRONTIERS MEDIA SA, 2022)
Background: The cognitive and neuropsychiatric deficits present in patients with behavioral variant frontotemporal dementia (bvFTD) are associated with loss of functionality in the activities of daily living (ADLs). The ...
Educational bias in the assessment of severe dementia: Brazilian cutoffs for severe Mini-Mental State Examination
(Academia Brasileira de Neurologia - ABNEURO, 2014-04-01)
Cognitive assessment in advanced stages of Alzheimer’s disease (AD) is limited by the imprecision of most instruments.Objective:To determine objective cognitive responses in moderate and severe AD patients by way of the ...
Uma intervenção psicoeducativa com cuidadores de idosos com demência
(Universidade Federal de São CarlosBRUFSCarPrograma de Pós-Graduação em Psicologia - PPGPsi, 2010-02-26)
The ageing of the Brazilian population comes accompanied by a growing number of cases of dementia, especially cases involving Alzheimer‟s disease, as the incidence of neurodegenerative diseases is directly related ...
Mapping the neuroanatomy of functional decline in Alzheimer’s disease from basic to advanced activities of daily living.
Background Impairments in activities of daily living (ADL) are a criterion for Alzheimer’s disease (AD) dementia. However, ADL gradually decline in AD, impacting on advanced (a-ADL, complex interpersonal or social functioning), ...
Mapping the neuroanatomy of functional decline in Alzheimer’s disease from basic to advanced activities of daily living.
Background Impairments in activities of daily living (ADL) are a criterion for Alzheimer’s disease (AD) dementia. However, ADL gradually decline in AD, impacting on advanced (a-ADL, complex interpersonal or social functioning), ...
Prevalência e fatores associados às alterações neurocognitivas em pessoas vivendo com HIV/AIDS
(Universidade Federal de São Paulo (UNIFESP), 2018-09-21)
Introduction: It is now known that human immunodeficiency virus (HIV) is the main
responsible for the development of neurocognitive disorder in individuals under 40
years. The development of antiretrovirals, the understanding ...
Ginkgo biloba as an alternative medicine in the treatment of anxiety in dementia and other psychiatric disorders
(2017-04-01)
Background: Mental disorders are the most common health problems in the worldwide population. Current medicines against these conditions have undesired side effects or limited effectiveness. These disadvantageous pharmacological ...
Multimodal mechanisms of human socially reinforced learning across neurodegenerative diseases
(Oxford University Press, 2021-03)
Social feedback can selectively enhance learning in diverse domains. Relevant neurocognitive mechanisms have been studied mainly in healthy persons, yielding correlational findings. Neurodegenerative lesion models, coupled ...