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Stoichiometry for activation of neuronal alpha7 nicotinic receptors.
(National Academy Of Sciences, 2013-11)
Neuronal 7 nicotinic receptors elicit rapid cation influx in response to acetylcholine (ACh) or its hydrolysis product choline. They contribute to cognition, synaptic plasticity, and neuroprotection, and have been implicated ...
Stoichiometry for activation of neuronal alpha7 nicotinic receptors
(National Academy of Sciences, 2013-12)
Neuronal α7 nicotinic receptors elicit rapid cation influx in response to acetylcholine (ACh) or its hydrolysis product choline. They contribute to cognition, synaptic plasticity, and neuroprotection and have been implicated ...
Effects of carbachol on rat Sertoli cell proliferation and muscarinic acetylcholine receptors regulation: an in vitro study
(Elsevier B.V., 2004-08-20)
The aim of the present work was to study the effect of muscarinic agonist on cell proliferation and muscarinic acetylcholine receptors (mAChRs) regulation in rat Sertoli cells. Primary cultures of Sertoli cells were obtained ...
Effects of combined cholinergic-purinergic block upon cat carotid body chemoreceptors in vitro
(ELSEVIER SCIENCE BV, 2007)
Since acetylcholine (ACh) and ATP have been proposed as excitatory co-transmitters at synapses between glomus cells and sensory nerve endings of the carotid body (CB), we tested such hypothesis by studying the effects of ...
Resolution of complex fluorescence spectra of lipids and nicotinic acetylcholine receptor by multivariate analysis reveals protein-mediated effects on the receptor's immediate lipid microenvironment
(Springer, 2008-12)
Analysis of fluorescent spectra from comp lex biological systems containing various fluorescent probes with overlapping emissi on bands is a challenging task. Valuable information can be extracted from the full spectra, ...
(−)-Reboxetine inhibits muscle nicotinic acetylcholine receptors by interacting with luminal and non-luminal sites
(Elsevier, 2013-07)
The interaction of (−)-reboxetine, a non-tricyclic norepinephrine selective reuptake inhibitor, with muscle-type nicotinic acetylcholine receptors (AChRs) in different conformational states was studied by functional and ...
Is the antidepressant activity of selective serotonin reuptake inhibitors mediated by nicotinic acetylcholine receptors?
(Molecular Diversity Preservation International, 2021-04)
It is generally assumed that selective serotonin reuptake inhibitors (SSRIs) induce antidepressant activity by inhibiting serotonin (5-HT) reuptake transporters, thus elevating synaptic 5-HT levels and, finally, ameliorates ...
Conformational and stereoeletronic investigations of muscarinic agonists of acetylcholine by NMR and theoretical calculations
(Elsevier Science BvAmsterdamHolanda, 2012)
The local anaesthetics proadifen and adiphenine inhibit nicotinic receptors by different molecular mechanisms
(Wiley Blackwell Publishing, Inc, 2009-07)
Background and purpose: Many local anaesthetics are non-competitive inhibitors of nicotinic receptors (acetylcholine receptor, AChR). Proadifen induces a high-affinity state of the receptor, but its mechanism of action and ...