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Protective axis of the renin-angiotensin system in the brain
(Portland Press, 2014-09)
The RAS (renin-angiotensin system) is composed of two arms: the pressor arm containing AngII (angiotensin II)/ACE (angiotensin-converting enzyme)/AT1Rs (AngII type 1 receptors), and the depressor arm represented by Ang-(1-7) ...
Envolvimento das cininas na dor do tipo fibromialgia induzida por reserpina e o efeito dos inibidores da enzima conversora de angiotensina I em camundongos
(Universidade Federal de Santa MariaBrasilBioquímicaUFSMPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica ToxicológicaCentro de Ciências Naturais e Exatas, 2019-03-29)
Fibromyalgia is a chronic disease potentially disabling, characterized by widespread pain and a range of comorbidities as hypertension, besides not having specific pathophysiology or appropriate treatment. Evidence has ...
Expression of angiotensin I-converting enzymes and bradykinin B-2 receptors in mouse inner medullary-collecting duct cells
(Elsevier B.V., 2008-02-01)
We described in mouse inner medullary-collecting duct cells (m1MCD-3) the somatic and the N-domain ACE synthesis and its interaction with the kallikrein-kinin system co-localized in the same cells. We purified two ACE forms ...
La enzima convertidora de angiotensina 2 como receptor del SARS-CoV-2
(Universidad de Talca (Chile). Escuela de Tecnología Médica., 2023)
Myelopoiesis modulation by ACE hyperfunction in kinin B-1 receptor knockout mice: Relationship with AcSDKP levels
(Elsevier B.V., 2010-03-30)
Angiotensin I-converting enzyme (ACE), a common element of renin-angiotensin system (RAS) and kallikrein-kinin system (KKS), is involved in myelopoiesis modulation, mainly by cleaving the tetrapeptide N-acetyl-seryl-aspa ...
ACE2 and vasoactive peptides: Novel players in cardiovascular/renal remodeling and hypertension
(2015)
The renin–angiotensin system (RAS) is a key component of cardiovascular physiology and homeostasis due to its influence on the regulation of electrolyte balance, blood pressure, vascular tone and cardiovascular remodeling. ...
The integrin binding peptide, atn-161, as a novel therapy for SARS-CoV-2 infection
Many efforts to design and screen therapeutics for the current severe acute respiratory
syndrome coronavirus (SARS-CoV-2) pandemic have focused on inhibiting viral host cell entry
by disrupting ACE2 binding with the ...
Contribution of spinal inhibitory receptors in heterosegmental antinociception induced by noxious stimulation
(Blackwell Publishing LtdOxfordInglaterra, 2003)
Aerobic Exercise Training-Induced Left Ventricular Hypertrophy Involves Regulatory MicroRNAs, Decreased Angiotensin-Converting Enzyme-Angiotensin II, and Synergistic Regulation of Angiotensin-Converting Enzyme 2-Angiotensin (1-7)
(LIPPINCOTT WILLIAMS & WILKINS, 2011)
Aerobic exercise training leads to a physiological, nonpathological left ventricular hypertrophy; however, the underlying biochemical and molecular mechanisms of physiological left ventricular hypertrophy are unknown. The ...