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Molecular modeling of the a9a10 nicotinic acetylcholine receptor subtype
(Elsevier Ltd., 2008-10-25)
This study reports the comparative molecular modeling, docking and dynamic simulations of human
a9a10 nicotinic acetylcholine receptors complexed with acetylcholine, nicotine and a-conotoxin RgIA,
using as templates the ...
Geographic differences in the distribution of molecular subtypes of breast cancer in Brazil
(BMC, 2014-08-29)
Abstract
Background
To compare the distribution of the intrinsic molecular subtypes of breast cancer based on immunohistochemical profile in the five major geographic regions ...
A Density Functional Theory Study Of The Relationships Between Electronic Structure And Metabotropic Glutamate Receptor Subtype 5 Affinity Of 2- Amino- And 2-Halothiazole Derivatives
(2014)
We carried out an investigation and analysis of the relationships between the electronic structure and
the metabotropic glutamate receptor subtype 5 affinity for a series of 2-amino- and 2-halothiazole derivatives
using ...
Dibenzofuranylethylamines as 5-HT2A/2C receptor agonists
(American Chemical Society, 2020)
The human 5-HT2 receptor subtypes have high sequence identity in their orthosteric ligand-binding domain, and many agonists are poorly selective between the S-HT(2A )and 5-HT2C subtypes. Nevertheless, their activation is ...
Functional antagonism of beta-adrenoceptor subtypes in the catecholamine-induced automatism in rat myocardium
(Wiley-blackwellMaldenEUA, 2011)
Effects of intracerebroventricular injections of losartan or PD123319 on arterial pressure and heart rate of sodium replete and sodium deplete rats
(1996-10-08)
Angiotensin II (Ang II) non-peptide antagonists were injected i.c.v. (6.25-200 nmol, n = 5-8 rats/group): In sodium replete rats, losartan (AT1 receptor antagonist) induced an increase in mean arterial pressure (MAP) and ...
Effects of intracerebroventricular injections of losartan or PD123319 on arterial pressure and heart rate of sodium replete and sodium deplete rats
(1996-10-08)
Angiotensin II (Ang II) non-peptide antagonists were injected i.c.v. (6.25-200 nmol, n = 5-8 rats/group): In sodium replete rats, losartan (AT1 receptor antagonist) induced an increase in mean arterial pressure (MAP) and ...
Expression and localization of muscarinic acetylcholine receptor subtypes in rat efferent ductules and epididymis
(Springer, 2006-01-01)
The expression of muscarinic acetylcholine receptor (mAChR) subtypes (M-1-M-5) was studied in the rat efferent ductules and epididymis at the mRNA and protein levels. the relative abundance of each mAChR transcript subtype ...
Structure-Based Approach for the Study of Estrogen Receptor Binding Affinity and Subtype Selectivity
(AMER CHEMICAL SOC, 2008)
Estrogens exert important physiological effects through the modulation of two human estrogen receptor (hER) subtypes, alpa (hER alpha) and beta (hER beta). Because the levels and relative proportion of hER alpha and hER ...
HETEROGENOUS ENDOTHELIN RECEPTORS MEDIATE RELAXATION and CONTRACTION in the GUINEA-PIG ILEUM
(Elsevier B.V., 1995-10-24)
IRL1620, a specific endothelin ET(B) receptor agonist, induced relaxation followed by contraction in the guinea-pig ileum, as did endothelin-1. Both components of the response were concentration-dependent in the range ...