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How does growth hormone releasing hexapeptide self-assemble in nanotubes?
(Royal Society of Chemistry, 2014-11)
Growth hormone releasing peptide, GHRP-6, a hexapeptide (His-(D-Trp)-Ala-Trp-(D-Phe)-Lys-NH2, MW = 872.44 Da) that belongs to a class of synthetic growth hormone secretagogues, can stimulate growth hormone secretion from ...
Molecular dynamics simulation of α-melanocyte stimulating hormone in a water-membrane model interface
(1999)
The conformation of the tridecapeptide α-melanocyte stimulating hormone in the presence of a double water-membrane interface was studied by molecular dynamics simulation, using the computational package THOR. In this program ...
Gastrointestinal hormones controlling energy homeostasis and their potential role in obesity
(Springer, 2018)
Gastrointestinal (GI) hormones are a family of peptides secreted by endocrine cells located in the GI tract. Currently, GI hormones group more than 50 hormone genes that give rise to a multitude of bioactive peptides. All ...
Growth hormone response to growth hormone-releasing peptide-2 in growth hormone-deficient Little mice
(Faculdade de Medicina / USP, 2012)
OBJECTIVE: To investigate a possible direct, growth hormone-releasing, hormone-independent action of a growth hormone secretagogue, GHRP-2, in pituitary somatotroph cells in the presence of inactive growth hormonereleasing ...
From growth hormone-releasing peptides to ghrelin: discovery of new modulators of GH secretion
(Sociedade Brasileira de Endocrinologia e Metabologia, 2006-02-01)
Growth hormone (GH)-releasing hormone and somatostatin modulate GH secretion. A third mechanism has been discovered in the last decade, involving the action of GH secretagogues. Ghrelin is a new acylated peptide produced ...
Growth hormone (GH) responses to GH-releasing peptide and to GH-releasing hormone in GH-deficient children
(1995)
The GH-releasing peptides (GHRPs) are a family of hexa- and heptapeptides that specifically stimulate GH secretion in normal adults and children. They would be an attractive potential form of therapy for GH deficiency (GHD) ...