Buscar
Mostrando ítems 41-50 de 134
Knockdown of Myo-Inositol transporter SMIT1 normalizes cholinergic and glutamatergic function in an immortalized cell line established from the cerebral cortex of a trisomy 16 fetal mouse, an animal model of human trisomy 21 (Down Syndrome)
(Springer, 2017)
The Na+/myo-inositol cotransporter (SMIT1) is overexpressed in human Down syndrome (DS) and in trisomy 16 fetal mice (Ts16), an animal model of the human condition. SMIT1 overexpression determines increased levels of ...
Envenomations by Bothrops and Crotalus Snakes Induce the Release of Mitochondrial Alarmins
(PLoS Negl Trop Dis 6(2): e1526, 2012-02-21)
Skeletal muscle necrosis is a common manifestation of viperid snakebite envenomations. Venoms from snakes of the genus Bothrops, such as that of B. asper, induce muscle tissue damage at the site of venom injection, provoking ...
Envenomations by Bothrops and Crotalus Snakes Induce the Release of Mitochondrial Alarmins
(PLoS Negl Trop Dis 6(2): e1526, 2012-02-21)
Skeletal muscle necrosis is a common manifestation of viperid snakebite envenomations. Venoms from snakes of the genus Bothrops, such as that of B. asper, induce muscle tissue damage at the site of venom injection, provoking ...
Small-molecule aggregation inhibitors reduce excess amyloid in a trisomy 16 mouse cortical cell line
(Sociedad de Biología de Chile, 2008)
Efeitos determinados pela amitriptilina, administrada pela via subaracnóidea, sobre a medula e as meninges: estudo experimental em cães
(Universidade Estadual Paulista (Unesp), 2008-10-21)
A amitriptilina é o protótipo dos antidepressivos tricíclicos, classe de fármaco muito utilizada no tratamento da dor neuropática. Tem por propriedade principal a inibição da recaptação de serotonina e noradrenalina, além ...
Efeitos do parecoxibe subaracnoideo sobre a medula espinal e as meninges de coelhos
(Universidade Estadual Paulista (Unesp), 2018-02-16)
Introdução: O parecoxibe, um pró-fármaco hidrolisado à valdecoxibe, é um antagonista da COX-2 com intensa atividade anti-inflamatória e analgésica. Embora muitos estudos tenham sido realizados indicando a eficácia dos ...
Efeitos determinados pela amitriptilina, administrada pela via subaracnóidea, sobre a medula e as meninges: estudo experimental em cães
(Universidade Estadual Paulista (UNESP), 2014)
Efeitos determinados pela amitriptilina, administrada pela via subaracnóidea, sobre a medula e as meninges: estudo experimental em cães
(Universidade Estadual Paulista (Unesp), 2014)
Worsening of memory deficit induced by energy-dense diet in a rat model of early-Alzheimer's disease is associated to neurotoxic Aβ species and independent of neuroinflammation
(Elsevier Science, 2017-03)
Diet is a modifiable risk factor for Alzheimer's disease (AD), but the mechanisms linking alterations in peripheral metabolism and cognition remain unclear. Since it is especially difficult to study long-term effects of ...