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High cholesterol diet effects on ischemia- reperfusion injury of the heart
(National Research Council Canada-NRC Research Press, 2012-09)
Ischemic heart disease is the leading cause of morbi-mortality in developed countries. Both ischemia-reperfusion injury and mechanisms of cardioprotection have been studied for more than 50 years. It is known that the ...
Antioxidantes enterais em lesões de isquemia e reperfusão em ratosEnteral antioxidants in ischemia/reperfusion injuries in rats
(Colégio Brasileiro de Cirurgiões, 2011)
Dexmedetomidine preconditioning activates pro-survival kinases and attenuates regional ischemia/reperfusion injury in rat heart
(ELSEVIER, 2012-04)
Pharmacological preconditioning limits myocardial infarct size after ischemia/reperfusion. Dexmedetomidine is an alpha(2)-adrenergic receptor agonist used in anesthesia that may have cardioprotective properties against ...
Effect of NF kappa B Inhibition by CAPE on Skeletal Muscle Ischemia-Reperfusion Injury
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2009)
Background/Aims. Nuclear factor kappa B (NF kappa B) plays important role in the pathogenesis of skeletal muscle ischemia/reperfusion (I/R) injury. Caffeic acid phenyl ester (CAPE), a potent NF kappa B inhibitor, exhibits ...
Heart injury following intestinal ischemia reperfusion in rats is attenuated by association of ischemic preconditioning and adenosine
(Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2014-01-01)
PURPOSE: To investigate the effect of ischemic preconditioning (IPC) and adenosine as strategies to protect cardiac injury caused by intestinal IR in rats, based on increasing in adenosine bioavailability and improvement ...
Evaluation of potential changes in liver and lung tissue of rats in an ischemia-reperfusion injury model (modified pringle maneuver)
(Public Library Science, 2017-06-12)
In surgical procedures involving the liver, such as transplantation, resection, and trauma, a temporary occlusion of hepatic vessels may be required. This study was designed to analyze the lesions promoted by ischemia and ...
Effect of protective solutions and hydroxyethyl starch in the attenuation of the injuries of ischemia and reperfusion of splanchnic organs
(Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2015-06-01)
PURPOSE: Vogt´s antioxidant solution (red blood cells, Ringer's solution, sodium bicarbonate, mannitol, allopurinol and 50% glucose) or its modification including hydroxyethyl starch (HES) were tested for the prevention ...
Comparative study between trimetazidine and ice slush hypothermia in protection against renal ischemia/reperfusion injury in a porcine model
(Brazilian Soc Urol, 2011-09-01)
Purpose: The aim of the study was to compare the effects of renal ice slush hypothermia and the use of trimetazidine in the protection against ischemia/reperfusion (I/R) injury.Materials and Methods: Fifteen farm pigs were ...