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Prohibition, regulation or free market: a mapping of Colombian people’s perspectives regarding national drug policies
(2015-02-15)
Colombian laypersons’ perspectives regarding actual and potential drug policies
were examined. Adults (N = 395) aged 18–68 and living in Bogota were presented
with 24 vignettes that were composed according to two ...
Correlation Between Testosterone And Psa Kinetics In Metastatic Prostate Cancer Patients Treated With Diverse Chemical Castrations
(SAGE PUBLICATIONS INCTHOUSAND OAKS, 2015)
Pharmacokinetics of hydroxymethylnitrofurazone and its parent drug nitrofurazone in rabbits
(Drug Metabolism Letters, 2013)
The prodrug hydroximethylnitrofurazone (NFOH) presents antichagasic activity with greatly reduced toxicity compared to its drug matrix nitrofurazone (NF). Besides these new characteristics, the prodrug was more active ...
Novel protease inhibitor-loaded Nanoparticle-in-Microparticle Delivery System leads to a dramatic improvement of the oral pharmacokinetics in dogs
(Elsevier, 2015-01)
With the advent of the Highly Active Antiretroviral Therapy, the morbidity and the mortality associated to HIV have been considerably reduced. However, 35-40 million people bear the infection worldwide. One of the main ...
Pharmacokinetics of hydroxymethylnitrofurazone and its parent drug nitrofurazone in rabbits
(2013-01-01)
The prodrug hydroximethylnitrofurazone (NFOH) presents antichagasic activity with greatly reduced toxicity compared to its drug matrix nitrofurazone (NF). Besides these new characteristics, the prodrug was more active ...
Avaliação biológica de implantes biodegradáveis contendo ciclosporina (A) de administração intravítrea
(Universidade Federal de Minas GeraisUFMG, 2011-05-25)
The treatment of posterior ocular disease is limited once the conventional forms of drug administration fail to provide therapeutic levels drug to the vitreous, retina and choroids. The biodegradable polym ers intraocular ...
Vitreous pharmacokinetics and electroretinographic findings after intravitreal injection of acyclovir in rabbits
(HOSPITAL CLINICAS, UNIV SAO PAULOSAO PAULO, 2012)
OBJECTIVES: Acute retinal necrosis is a rapidly progressive and devastating viral retinitis caused by the herpesvirus family. Systemic acyclovir is the treatment of choice; however, the progression of retinal lesions ceases ...
The anticancer drug tamoxifen is active against Trypanosoma cruzi in vitro but ineffective in the treatment of the acute phase of Chagas disease in mice
(Instituto Oswaldo Cruz, Ministério da Saúde, 2010)
The activity of the antineoplastic drug tamoxifen was evaluated against Trypanosoma cruzi. In vitro activity was determined against epimastigote, trypomastigote and amastigote forms of CL14, Y and Y benznidazole resistant ...