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U-Omp19 from Brucella abortus increases dmLT immunogenicity and improves protection against Escherichia coli heat-labile toxin (LT) oral challenge
(Elsevier, 2020-07)
Acute diarrhea disease caused by bacterial infections is a major global health problem. Enterotoxigenic Escherichia coli (ETEC) is one of the top causes of diarrhea-associated morbidity and mortality in young children and ...
Using of phosphate nanocomposites for therapeutics in melanoma model
(Universidade Federal de Minas GeraisBrasilICB - INSTITUTO DE CIÊNCIAS BIOLOGICASPrograma de Pós-Graduação em Biologia CelularUFMG, 2021-09-20)
The incidence rates of melanoma have been increasing dramatically in recent years. The search for strategies that increase therapeutic efficiency and reduce side effects is the focus of several studies today. The treatment ...
Poly(lactic acid-glycolic acid) nanoparticles markedly improve immunological protection provided by peptide P10 against murine paracoccidioidomycosis
(WILEY-BLACKWELL PUBLISHING, INC, 2010)
Background and purpose: The present study reports on the preparation and testing of a sustained delivery system for the immunomodulatory peptide P10 aimed at reducing the in vivo degradation of the peptide and the amount ...
Poly(lactic acid-glycolic acid) nanoparticles markedly improve immunological protection provided by peptide P10 against murine paracoccidioidomycosis
(Wiley-Blackwell, 2010-03-01)
Background and purpose:The present study reports on the preparation and testing of a sustained delivery system for the immunomodulatory peptide P10 aimed at reducing the in vivo degradation of the peptide and the amount ...
Vaccine design against chagas disease focused on the use of nucleic acids
(MDPI, 2022)
Chagas disease is caused by the protozoan Trypanosoma cruzi and is endemic to Central and South America. However, it has spread around the world and affects several million people. Treatment with currently available drugs ...
Histamine as a potential adjuvant to immuno and radiotherapy for cancer treatment: discovering new functions for the oldest biogenic amine
(Bentham Science Publishers, 2010-11)
Since histamine discovery in 1910, it has been recognized as a major mediator in gastric acid secretion and inflammation that is a main pathophysiological characteristic of allergy. For many years, drug development and ...
Desenvolvimento de nanoemulsão catiônica para incorporar a peçonha do escorpião Tityus serrulatus e avaliar eficácia do soro produzido a partir de imunização de camundongos
(Universidade Federal do Rio Grande do NorteBrasilUFRNPROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS DA SAÚDE, 2020-11-18)
Scorpion stings are major cause of envenoming by animals in endemic countries, like
Brazil. The scorpion antivenom is product that is able to neutralize and to protect
sensitive people. However, its production has been ...
Perspectivas da utilização de nanopartículas de quitosana na produção de vacinas
(Universidade Federal de Minas GeraisUFMG, 2015-02-23)
The development of new vaccines that are stable and economical, require few doses and may be administered using free needle systems is undoubtedly a global priority. Given this need, it is essential the development of new ...