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Dentate Gyrus Somatostatin Cells are Required for Contextual Discrimination During Episodic Memory Encoding
(Oxford Univ Press Inc, 2020-10)
Memory systems ought to store and discriminate representations of similar experiences in order to efficiently guide future decisions. This problem is solved by pattern separation, implemented in the dentate gyrus (DG) by ...
Memória contextual e estratégias de codificação em idosos com sintomas depressivos
(Pontifícia Universidade Católica do Rio Grande do SulPorto Alegre, 2007)
Contextual memory has been considered one aspect of cognitive functioning especially susceptible to the negative effects of aging on cognition. It has been verified that memory strategies could reduce memory deficits in ...
Memória contextual e estratégias de codificação em idosos com sintomas depressivos
(Pontifícia Universidade Católica do Rio Grande do SulPorto Alegre, 2007)
Contextual memory has been considered one aspect of cognitive functioning especially susceptible to the negative effects of aging on cognition. It has been verified that memory strategies could reduce memory deficits in ...
Efeitos do envelhecimento e da integridade funcional do córtex pré-frontal sobre a memória contextual e uso de estratégias de codificação
(Pontifícia Universidade Católica do Rio Grande do SulPorto Alegre, 2011)
Background: Age related reductions in contextual memory can impair daily functioning of older adults and have an important impact on their quality of life. Thus, the understanding of the neurobiological correlates of this ...
Efeitos do envelhecimento e da integridade funcional do córtex pré-frontal sobre a memória contextual e uso de estratégias de codificação
(Pontifícia Universidade Católica do Rio Grande do SulPorto Alegre, 2011)
Background: Age related reductions in contextual memory can impair daily functioning of older adults and have an important impact on their quality of life. Thus, the understanding of the neurobiological correlates of this ...
Effects of Hippocampal LIMK Inhibition on Memory Acquisition, Consolidation, Retrieval, Reconsolidation, and Extinction
(Humana Press, 2018-02)
Long-lasting changes in dendritic spines provide a physical correlate for memory formation and persistence. LIM kinase (LIMK) plays a critical role in orchestrating dendritic actin dynamics during memory processing, since ...
Calcineurin phosphatase as a negative regulator of fear memory in hippocampus: Control on nuclear factor-κB signaling in consolidation and reconsolidation
(Wiley, 2014-12)
Protein phosphatases are important regulators of neural plasticity and memory. Some studies support that the Ca2+/calmodulin-dependent phosphatase calcineurin (CaN) is, on the one hand, a negative regulator of memory ...
Regulation of Memory Formation by the Transcription Factor XBP1
(2016)
Contextual memory formation relies on the induction of new genes in the hippocampus. A polymorphism in the promoter of the transcription factor XBP1 was identified as a risk factor for Alzheimer's disease and bipolar ...
Envolvimento do córtex infralímbico na consolidação de memórias de medo contextual em ratos
(2021)
O córtex infralímbico (IL) é uma região crucial para a atenuação de memórias aversivas através da extinção. Estudos prévios demonstraram que lesão ou inativação dessa região antes da aquisição da memória torna as memórias ...
Sleep deprivation alters phosphorylated CREB levels in the amygdala: Relationship with performance in a fear conditioning task
(Elsevier B.V., 2013-01-01)
We investigated the relationship between deficits in fear memory induced by sleep deprivation and pCREB expression in the basal and central nuclei of the amygdala. Sleep deprivation reduced pCREB expression in the central ...