Buscar
Mostrando ítems 41-50 de 1491
Alterações genéticas de cistos e tumores odontogênicos
(Universidade Federal de Minas GeraisBrasilICB - DEPARTAMENTO DE PATOLOGIAPrograma de Pós-Graduação em PatologiaUFMG, 2019-12-10)
Odontogenic tumors and delevopmental cysts are rare and most of them show uncertain pathogenesis. The use of next generation sequencing techniques (NGS) help to identify pathogenic driver mutations of different tumors. ...
Determinants of differential functions of galectin-8 on T cells and tumoral cells : interplay of galectin-8 isoforms, integrin and growth factor signaling pathways.
(2014)
Galectins are a subfamily of lectins involved in a variety of cellular processes mainly related with the immune system and cancer. Galectins are secreted through unconventional mechanisms, because they lack a signal peptide, ...
Effects of glutamine on the nuclear factor-kappaB signaling pathway of murine peritoneal macrophages
(SPRINGER, 2010)
The aim of this study was to evaluate the effect of glutamine on the expression of proteins involved in the nuclear factor-kappaB (NF-kappa B) signaling pathway of murine peritoneal macrophages. Since glutamine is essential ...
Up-regulation of tumor necrosis factor-α pathway survival genes and of the receptor TNFR2 in gastric cancer
(2019-04-01)
BACKGROUND Gastric carcinogenesis can be induced by chronic inflammation triggered by Helicobacter pylori (H. pylori) infection. Tumor necrosis factor (TNF)-α and its receptors (TNFR1 and TNFR2) regulate important cellular ...
Emerging agents that target signaling pathways to eradicate colorectal cancer stem cells
(BioMed Central (BMC), 2022)
TNF-alpha acts in the hypothalamus inhibiting food intake and increasing the respiratory quotient - Effects on leptin and insulin signaling pathways
(Elsevier B.V., 2007-05-01)
Acting in the hypothalamus, tumor necrosis factor-alpha (TNF-alpha) produces a potent anorexigenic effect. However, the molecular mechanisms involved in this phenomenon are poorly characterized. In this study, we investigate ...
Downregulation of the Sonic Hedgehog/Gli pathway transcriptional target Neogenin-1 is associated with basal cell carcinoma aggressiveness
(Impact Journals Llc., 2017)
Basal Cell Carcinoma (BCC) is one of the most diagnosed cancers worldwide. It develops due to an unrestrained Sonic Hedgehog (SHH) signaling activity in basal cells of the skin. Certain subtypes of BCC are more aggressive ...
Galectins: Key players in the tumor microenvironment
(Elsevier, 2013)
Galectins are glycan‐binding proteins implicated in several biological activities such as intracellular signaling, cell‐cell communication, cellular proliferation and survival. These endogenous lectins have emerged as key ...